Results 41 to 50 of about 2,402,623 (312)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Clinical and Biological Features of Response in Resistant Neuroblastoma to 131I‐Metaiodobenzylguanidine Radiotherapy in the Anti‐GD2 Immunotherapy Era

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman, Katherine K. Matthay, Fabienne Hollinger, Catriona Black, Ann A. Lazar, Miguel Pampaloni, Steven G. DuBois, Kieuhoa T. Vo   +7 more
wiley   +1 more source

Modeling of Seismic Progressive Collapse Distribution in 3 Story Symmetric and Asymmetric Reinforced Concrete Buildings [PDF]

مجله مدل سازی در مهندسی, 2014
This paper models the 3D progressive collapse of a 3 story reinforced concrete symmetric/asymmetric building with different levels of mass eccentricity under earthquake loads.
somayyeh karimiyan, aboreza sarvghad moghadam   +1 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Impact of Various High Intensity Earthquake Characteristics on the Inelastic Seismic Response of Irregular Medium-Rise Buildings

Applied Sciences
In the twenty-first century, the seismic design of buildings seems to have become a fully recognized topic. There are guidelines and standards which should be taken into account by designers in seismic areas.
Filip Pachla, Tadeusz Tatara, Waseem Aldabbik   +2 more
doaj   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Effects of Diagonal Friction Dampers on Behavior of a Building

Applied Sciences, 2023
In this study, the effect of the friction damper location on the earthquake behavior of a building was investigated. Diagonal braced friction dampers were placed on different floors, and the changes in building behavior were examined. For this purpose, a
Emine Aydin, Elif Boru, Mert Gurbuz
doaj   +1 more source

Analysis of Temporal and Web Site References in History-related Tweets [PDF]

, 2017
peer reviewedHaving good knowledge and comprehension of history is believed to be important for a variety of reasons. In this paper we report the initial results of a large scale exploratory analysis of history-focused references in microblogs based on ...
Sumikawa, Yasunobu, DURING, Marten, Yasunobu Sumikawa, Marten Düring, Jatowt, Adam, Adam Jatowt   +5 more
core   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

Numerical Simulation of Wind-Induced Vibration Response Characteristics of High-Rise Buildings with Podiums

Buildings
High-rise building structures with podiums are widely present, and establishing a fast numerical prediction method to evaluate their wind-induced response characteristics is of great significance for engineering applications.
Guangbiao Jiang, Zeyan Chen, Hongxi Qin, Linlei Dong, Ao Tang   +4 more
doaj   +1 more source