Results 51 to 60 of about 749,885 (297)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Heteroscedasticity and interval effects in estimating beta: UK evidence

, 2011
The article compares beta estimates obtained from Ordinary Least Squares (OLS) regression with estimates corrected for heteroscedasticity of the error term using Autoregressive Conditional Heteroscedasticity (ARCH) models, for 145 UK shares.
Armitage, S., Brzeszczynski, Janusz, Seth Armitage, Brzeszczynski, J., Janusz Brzeszczynski, Armitage, Seth   +5 more
core   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Photonic Multiple Microwave Frequency Measurement Based on Frequency-to-Time Mapping

IEEE Photonics Journal, 2018
A photonic multiple microwave frequency measurement system is presented and demonstrated based on a swept frequency silicon microring resonator (MRR). The drop-port of a high-Q MRR is employed as a periodic narrowband scanning filter driven by a sawtooth
Feng Zhou, Hao Chen, Xu Wang, Linjie Zhou, Jianji Dong, Xinliang Zhang   +5 more
doaj   +1 more source

Industrial engineering applications in metrology: Job scheduling, calibration interval and average outgoing quality [PDF]

, 2013
This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel UniversityThis research deals with the optimization of metrology and calibration problems.
Al Reeshi, Mohammad Ahmad
core  

Functional inference for interval-censored data in proportional odds model with covariate measurement error

, 2014
It is common in regression analysis of failure time data, such as the AIDS Clinical Trail Group (ACTG) 175 clinical trial data, that the failure time (AIDS incidence time) is subject to interval-censoring and the covariate (baseline CD4 count) is subject
Wen, Chi-Chung; Chen, Yi-Hau
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

A survey on time interval measurement techniques and testing methods

, 2010
The most frequently utilized techniques for precise time interval measurements are discussed. By analyzing the characteristics of both published architectures and commercial Time-to-Digital Converters (TDCs), the most significant testing methods are also
CARBONE, Paolo, P. Carbone, A. Moschitta, P. Napolitano, MOSCHITTA, Antonio   +4 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Usando um voltímetro para medir tempo

Revista Brasileira de Ensino de Física
As vezes, para se medir um intervalo de tempo, é suficiente um cronômetro, outras vezes é preciso imaginar ou lançar mão de métodos indiretos. Neste trabalho exploramos um método indireto para medir intervalos de tempo baseado na curva de descarga de um ...
Roberto Hessel, Ângelo C. Perinotto
doaj   +1 more source