Results 51 to 60 of about 1,262,484 (349)
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
The Macroeconomy as a Network of Money-Flow Transfer Functions [PDF]
An introduction on A.W. Phillips’ "hydraulic" macroeconomic models is given. His (and others economists’) notion that a macroeconomy may reasonably be considered to have dynamics corresponding to a first order time lag transfer function, is justified in ...
Trond Andresen
doaj +1 more source
Thermal Performance of Structural Lightweight Concrete Composites for Potential Energy Saving
Residential consumption dominates the energy expenditure of heating and cooling systems, especially in tropical climates where building envelopes play an important role in energy efficiency.
Yeong Huei Lee +7 more
doaj +1 more source
The Lick AGN Monitoring Project: Reverberation Mapping of Optical Hydrogen and Helium Recombination Lines [PDF]
We have recently completed a 64-night spectroscopic monitoring campaign at the Lick Observatory 3-m Shane telescope with the aim of measuring the masses of the black holes in 12 nearby (z < 0.05) Seyfert 1 galaxies with expected masses in the range ~10^6-
Aaron J. Barth +43 more
core +4 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The temperature state of outer space devices is influenced by the heat flow outside the space. Although traditional numerical simulation analysis methods are highly accurate, they are time-consuming and not conducive for researchers to quickly assess the
Jing Qian, Jing Qian, Liwei Sun
doaj +1 more source
Quasar optical variability: searching for interband time delays [PDF]
Aims. The main purpose of this paper is to study time delays between the light variations in different wavebands for a sample of quasars. Measuring a reliable time delay for a large number of quasars may help constraint the models of their central ...
Sundar Rajan, B., Susinder Rajan, G.
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Smoothing is essential to many oceanographic, meteorological and hydrological applications. The interval smoothing problem updates all desired states within a time interval using all available observations.
A Gelb +17 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

