Results 61 to 70 of about 1,198,360 (328)

Dynamics of Feedback Systems with Time Lag [PDF]

open access: yes, 1985
Here are four examples of autonomous functional differential equations with time lags which have been used for modelling. First, the logistic equation with delay in the growth-limiting factor $$ \left( {dn/dt} \right)(t) \equiv \dot{n}(t) = rn(t)\left[ {1 - n\left( {t - \tau } \right)/K} \right] $$ (1) proposed by the biologist HUTCHINSON [17]
Walther, Hans-Otto   +1 more
openaire   +4 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

A Simple Method for Predicting Intensity Change Using the Peak Time Lag Between Lightning and Wind in Tropical Cyclones

open access: yesGeophysical Research Letters, 2021
Using lightning data from the World‐Wide Lightning Location Network (WWLLN) and tracking data for Tropical Cyclones (TCs) from the China Meteorological Administration (CMA), the relationship between the peak time lag (Tlag) and the wind intensity change ...
Xiangzhen Kong   +4 more
doaj   +1 more source

Properties of unique hard X-ray dips observed from GRS 1915+105 and IGR J17091-3624 and their implications

open access: yes, 2013
We report a comprehensive study on spectral and timing properties of hard X-ray dips uniquely observed in some so-called variability classes of the micro-quasars GRS 1915+105 and IGR J17091-3624.
Bhattacharyya, Sudip   +5 more
core   +2 more sources

The changing X-ray time lag in MCG-6-30-15 [PDF]

open access: yes, 2014
MCG-6-30-15 is one of the most observed Narrow Line Seyfert 1 galaxies in the X-ray band. In this paper we examine the X-ray time lags in this source using a total of 600 ks in observations (440 ks exposure) taken with the XMM-Newton telescope (300 ks in
Alston, W.   +8 more
core   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

The timeliness of the effects of monetary policy: the new evidence from econometric models

open access: yesPSL Quarterly Review, 2014
The usefulness of monetary policy for smoothing out cyclical movements or keeping the economy on its desired growth path has long been a matter of debate. In the past, monetary policy was often condemned as being ineffectual. More recently, discretionary
W.H. WHITE
doaj   +1 more source

Reverberation Measurements of the Inner Radius of the Dust Torus in Nearby Seyfert 1 Galaxies

open access: yes, 2005
The most intense monitoring observations yet made in the optical (UBV) and near-infrared (JHK) wave bands were carried out for nearby Seyfert1 galaxies of NGC 5548, NGC 4051, NGC 3227, and NGC 7469.
Antonucci R.   +16 more
core   +2 more sources

Early phase pharmacokinetics but not pharmacodynamics are influenced by propofol infusion rate [PDF]

open access: yes, 2009
Background: Conventional compartmental pharmacokinetic models wrongly assume instantaneous drug mixing in the central compartment, resulting in a flawed prediction of drug disposition for the first minutes, and the flaw affects pharmacodynamic modeling ...
Hagihira, Satoshi   +5 more
core   +2 more sources

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