Results 71 to 80 of about 1,258,485 (255)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Response of the Normalized Difference Vegetation Index (NDVI) to Snow Cover Changes on the Qinghai–Tibet Plateau

open access: yesRemote Sensing
The eco-hydrological process related to vegetation on the Qinghai–Tibet Plateau is special, and the impact of snow cover on the growth of vegetation is unique and important.
Yuantao Zhou   +3 more
doaj   +1 more source

Time lag between prompt optical emission and gamma-rays in GRBs

open access: yes, 2006
The prompt optical emission contemporaneous with the $\gamma$-rays from $\gamma$-ray bursts (GRBs) carries important information on the central engine and explosion mechanism. We study the time lag between prompt optical emission and $\gamma$-rays in GRB
Akerlof   +12 more
core   +1 more source

Comparison of time/phase lags in the hard state and plateau state of GRS 1915+105 [PDF]

open access: yes, 2013
We investigate the complex behavior of energy- and frequency-dependent time/phase lags in the plateau state and the radio-quiet hard state of GRS 1915+105.
Misra, Ranjeev   +4 more
core   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Water-Covered Roof Versus Inverted Flat Roof on the Mediterranean Coast: A Comparative Study of Thermal and Energy Behavior

open access: yesApplied Sciences, 2020
Reservoir, or water-collecting roofs present greater thermal inertia than inverted flat roofs due to the mass of water they contain. This feature gives them better thermal performance and leads to greater stability in the indoor air temperature Ti and ...
Almudena Espinosa-Fernández   +2 more
doaj   +1 more source

Quasar optical variability: searching for interband time delays [PDF]

open access: yes, 2006
Aims. The main purpose of this paper is to study time delays between the light variations in different wavebands for a sample of quasars. Measuring a reliable time delay for a large number of quasars may help constraint the models of their central ...
Sundar Rajan, B., Susinder Rajan, G.
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The Lick AGN Monitoring Project: Reverberation Mapping of Optical Hydrogen and Helium Recombination Lines [PDF]

open access: yes, 2010
We have recently completed a 64-night spectroscopic monitoring campaign at the Lick Observatory 3-m Shane telescope with the aim of measuring the masses of the black holes in 12 nearby (z < 0.05) Seyfert 1 galaxies with expected masses in the range ~10^6-
Aaron J. Barth   +43 more
core   +4 more sources

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

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