Results 101 to 110 of about 17,407,057 (195)

Space-Time Trellis and Space-Time Block Coding Versus Adaptive Modulation and Coding Aided OFDM for Wideband Channels

open access: yes, 2006
—The achievable performance of channel coded spacetime trellis (STT) codes and space-time block (STB) codes transmitted over wideband channels is studied in the context of schemes having an effective throughput of 2 bits/symbol (BPS) and 3 BPS.
Liew, T.H., Hanzo, L.
core   +1 more source

Cascaded Fiber-Optic Time Synchronization System with Different Modulation Format

open access: yesPhotonics
High-precision time and frequency transfer plays a pivotal role in metrology, geodesy, deep-space exploration and other scientific applications. Based on current time synchronization research, extending point-to-point schemes into a wide-area network can
Zhaohui Wang   +4 more
doaj   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Inspect the Time Lag in Galactic Cosmic-Ray Solar Modulation

open access: yesThe Astrophysical Journal
It is well known that there is a time lag between the solar activity and the galactic cosmic-ray flux. How to accurately describe this delay is the key problem in making precise predictions of cosmic-ray flux.
Xiaojian Song, Xi Luo, Zhaomin Wang
doaj   +1 more source

On the Design of Near-Optimal Generalized Block-Based Spatial Modulation With Low Detection Complexity

open access: yesIEEE Open Journal of Signal Processing
Spatial Modulation (SM) and Generalized Spatial Modulation (GSM) have attracted significant attention in the development of spectrally and energy-efficient transmission schemes for multiple-input multiple-output (MIMO) systems.
Yen-Ming Chen   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Adaptive Dead-Time Modulation Scheme for Bidirectional LLC Resonant Converter in Energy Router

open access: yesCSEE Journal of Power and Energy Systems
Although the dead-time optimization design of resonant converters has been widely researched, classical design methods focus more on achieving zero-voltage switching (ZVS) operation.
Chenghao Sun   +4 more
doaj   +1 more source

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