Results 41 to 50 of about 36,560 (265)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Ordinary People and the Great Time of Troubles: Homestead Ownership in Veliky Novgorod and Yaroslavl in 1606–1618

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2019
There are a lot of scientific papers about Russian cities between 16th and 17th centuries, however the discussion is focused mainly on economic activities and duties of citizens.
Vladimir A. Arakcheev
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Captain Jacques Margeret: a Remarkable Huguenot Soldier in Russia’s Time of Troubles

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2019
. Captain Jacques Margeret (fl. 1591-1621), a brave and highly intelligent French Huguenot soldier, was an active observer-participant in the Time of Troubles who contributed to Russia’s military modernization.
Chester S. L. Dunning
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Continuing the Traditions of Studying the Time of Troubles

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2019
The traditions of studying the Time of Troubles in Volgograd: history and modernity.
Vasiliy V. Tarakanov
doaj  

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Reflection of the events of the Time of Troubles of the early 17th century in the legends about the ancestors of Kayum Nasyri

open access: yesИз истории и культуры народов Среднего Поволжья
This article examines the legends about Gabderazzak, the ancestor of the famous Tatar scholar and educator Kayum Nasyri (1825–1902). The legends were written down by Kayum Nasyri himself from the words of the residents of the village of Verkhnie Shirdany.
Maksum Maratovich Akchurin
doaj   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

“Gold-Boiling” Mangazeya — A Legendary City of the Russian Arctic

open access: yesАрктика и Север
For centuries, the Russians have been persistently developing the northern territories, moving further and further eastwards both by land and by sailing across the northern seas.
Konstantin V. Lobanov   +1 more
doaj   +1 more source

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