Results 41 to 50 of about 44,178 (295)

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

The figure of the impostor to the throne in Russian political culture: Between sacralization and mimesis

open access: yesSign Systems Studies, 2017
Proceeding from materials relating to the “Time of Troubles”, this article examines the phenomenon of imposture (samozvanchestvo) as one of the symbols of Russian political history from the early 17th to the mid-19th century.
Ilya Kalinin
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Human security and casualty counting in Ulster: Towards a peaceful and just solution

open access: yesJournal of Global Faultlines, 2021
The Troubles have spread heartbreak and misery across Northern Ireland, mainland Britain, and Europe for 50 years, claiming the lives of thousands and victimizing tens of thousands.
Sally Browne
doaj   +1 more source

Time of Troubles: Arnold J. Toynbee's Twentieth Century

open access: yes, 2014
Arnold J. Toynbee (1889-1975) has long been neglected or discounted by scholars of international relations and historians of international thought. Yet his contributions to International Affairs, as well as his Surveys of international affairs and his A ...
Hall, Ian
core   +2 more sources

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Ordinary People and the Great Time of Troubles: Homestead Ownership in Veliky Novgorod and Yaroslavl in 1606–1618

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения, 2019
There are a lot of scientific papers about Russian cities between 16th and 17th centuries, however the discussion is focused mainly on economic activities and duties of citizens.
Vladimir A. Arakcheev
doaj   +1 more source

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