Results 51 to 60 of about 481,932 (293)

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni   +19 more
wiley   +1 more source

Quantification of Densities of Bacterial Endosymbionts of Insects by Real-time PCR

open access: yesBio-Protocol, 2017
Increased attention has been paid to the endosymbiotic bacteria of insects. Because most insect endosymbionts are uncultivable, quantitative PCR (qPCR) is a practical and convenient method to quantify endosymbiont titers.
Daisuke Kageyama
doaj   +1 more source

Identification of rare atypical BCR-ABL1 transcript: A case report

open access: yesIndian Journal of Pathology and Microbiology, 2023
CML is characterized by the presence of a BCR-ABL1 fusion transcript. Several guidelines have been published for its detection and molecular monitoring.
Jayesh Saha   +3 more
doaj   +1 more source

Embedding Population Dynamics Models in Inference

open access: yes, 2007
Increasing pressures on the environment are generating an ever-increasing need to manage animal and plant populations sustainably, and to protect and rebuild endangered populations.
Buckland, Stephen T.   +4 more
core   +3 more sources

NFDI MatWerk Ontology (MWO): A BFO‐Compliant Ontology for Research Data Management in Materials Science and Engineering

open access: yesAdvanced Engineering Materials, EarlyView.
This article presents the NFDI‐MatWerk Ontology (MWO), a Basic Formal Ontology‐based framework for interoperable research data management in materials science and engineering (MSE). Covering consortium structures, research data management resources, services, and instruments, MWO enables semantic integration, Findable, Accessible, Interoperable, and ...
Hossein Beygi Nasrabadi   +4 more
wiley   +1 more source

PRESENT-DAY MISSION PARTNERSHIPS

open access: yesActa Theologica, 2019
The centre of gravity of the church and of mission-sending has shifted from the North and West to the South and East. Currently, as many full-time cross-cultural missionaries are sent and supported by churches in Asia, Africa and Latin America as those ...
C van Engen
doaj   +1 more source

Nanodiamond Quantum Sensors for Probing Free Radical Biology

open access: yesAdvanced Functional Materials, EarlyView.
Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley   +1 more source

The Bleeding Time: Review of Basic Principle, Clinical Applications, and Laboratory Pitfalls

open access: yesSiriraj Medical Journal, 2016
The bleeding time is one of the oldest tests for primary hemostasis which is still performed nowadays.This test evaluates mainly the primary hemostatic function.
Chaicharoen Tantanate
doaj  

Relieving the fermionic and the dynamical sign problem: Multilevel Blocking Monte Carlo simulations [PDF]

open access: yes, 2001
This article gives an introduction to the multilevel blocking (MLB) approach to both the fermion and the dynamical sign problem in path-integral Monte Carlo simulations. MLB is able to substantially relieve the sign problem in many situations. Besides an
Egger, R., Mak, C. H.
core   +1 more source

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

open access: yesAdvanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy