Results 41 to 50 of about 439,101 (211)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Depression does not affect time perception and time-to-contact estimation
Frontiers in Psychology, 2014 Depressed patients frequently report a subjective slowing of the passage of time. However, experimental demonstrations of altered time perception in depressed patients are not conclusive. We added a timed action task (time-to-contact estimation, TTC) and
Daniel eOberfeld +3 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Quantifying uncertainty in time perception: A modified reproduction method
i-PerceptionIn time perception research, we typically measure how an observer perceives time intervals by collecting data from multiple trials with a single estimate recorded on each.
Jaume Boned, Joan López-Moliner
doaj +1 more source
How much time has passed? Ask your heart
Frontiers in Neurorobotics, 2014 Internal signals like one's heartbeats are centrally processed via specific pathways and both their neural representations as well as their conscious perception (interoception) provide key information for many cognitive processes.
Olga ePollatos +3 more
doaj +1 more source
PLoS ONE, 2023 We provide a novel way to correct the effective reproduction number for the time-varying amount of tests, using the acceleration index (Baunez et al., 2021) as a simple measure of viral spread dynamics.
Christelle Baunez +5 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Vibration reproduction of non-strengthen member by real time hybrid testing
Nihon Kikai Gakkai ronbunshuIndustrial vehicles such as construction machineries are exposed to severe vibration during use, which can cause structural damage. Currently, vibration endurance testing for non-strengthen members such as doors and covers, requires the assembly of the ...
Masataka KAWAGUCHI +4 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source