Results 191 to 200 of about 3,595,948 (318)

Space and Time Scales of Atmospheric Variability [PDF]

, 1981
Michael Stefanick
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Evolution of cyclic di-GMP signalling on a short and long term time scale. [PDF]

Microbiology (Reading), 2023
Römling U, Cao LY, Bai FW.
europepmc   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

Dendritic, delayed, stochastic CaMKII activation in behavioural time scale plasticity. [PDF]

Nature
Jain A, Nakahata Y, Pancani T, Watabe T, Rusina P, South K, Adachi K, Yan L, Simorowski N, Furukawa H, Yasuda R.   +10 more
europepmc   +1 more source

The Time Scale of Shallow Convective Self-Aggregation in Large-Eddy Simulations Is Sensitive to Numerics. [PDF]

J Adv Model Earth Syst, 2023
Janssens M, Vilà-Guerau de Arellano J, van Heerwaarden CC, van Stratum BJH, de Roode SR, Siebesma AP, Glassmeier F.   +6 more
europepmc   +1 more source

High-Precision Calibration of the Radiocarbon Time Scale, 500–2500 bc [PDF]

, 1986
Gordon W. Pearson, Minze Stuiver
openalex   +1 more source

The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity

Molecular Oncology, EarlyView.
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause, Rixa‐Mareike Köhn, Christian Ickes, Julia Lenger, Jonas Fischer, Sabrina Cappello, Ivan Bogeski   +6 more
wiley   +1 more source

Ensemble All Time-Scale Decomposition Method and Its Application in Bevel Gear Fault Diagnosis. [PDF]

Sensors (Basel)
Cheng Z, Yang Y, Duan C, Kang X, Cui J.
europepmc   +1 more source

CO₂ Reduction by Nanosecond-Plasma Discharges: Revealing the Dissociation's Time Scale and the Importance of Pulse Sequence. [PDF]

J Phys Chem C Nanomater Interfaces, 2023
Montesano C, Salden TPW, Martini LM, Dilecce G, Tosi P.   +4 more
europepmc   +1 more source