Results 191 to 200 of about 22,430,852 (308)
Formulation of a dynamic convective adjustment time-scale in the CESM1.2 and its influence on the Indian summer monsoon simulations. [PDF]
Sci RepPathak R, Sahany S, Mishra SK, Wang J.
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
A multi-time scale rolling optimization framework for low-carbon operation of CCHP microgrids with demand response integration. [PDF]
PLoS OneWang J, Cheng Z, Lu D, Zhu M, Zhang D.
europepmc +1 more source
Rising Star Monitor 2025: Decoding how fit young scale-ups are for future growth
The tenth edition of the Rising Star Monitor, an annual study by Deloitte Belgium in collaboration with the Vlerick Centre for Excellence in Scale-ups, once again charts how Belgian scale-ups are performing on crucial growth capabilities such as ...
Gialos, Panagiotis, Collewaert, Veroniek
core
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Extensive Backbone Cleavage Coverage of Intact Proteoforms in a Mass Range of 10-70 kDa by Integrating Electron, Collision, and Photon-Based Fragmentation Techniques during an Electrophoretic Time Scale. [PDF]
J Am Soc Mass SpectromWang Q +5 more
europepmc +1 more source