Results 61 to 70 of about 802,210 (308)

Some Opial-Type Inequalities on Time Scales

open access: yesAbstract and Applied Analysis, 2011
We will prove some dynamic inequalities of Opial type on time scales which not only extend some results in the literature but also improve some of them. Some discrete inequalities are derived from the main results as special cases.
S. H. Saker
doaj   +1 more source

Avoidance Control on Time Scales [PDF]

open access: yesJournal of Optimization Theory and Applications, 2010
We consider dynamic systems on time scales under the control of two agents. One of the agents desires to keep the state of the system out of a given set regardless of the other agent's actions. Leitmann's avoidance conditions are proved to be valid for dynamic systems evolving on an arbitrary time scale.
Pawłuszewicz, E., Torres, D.F.M.
openaire   +5 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

The Time Scale of Evolutionary Innovation

open access: yesPLoS Computational Biology, 2014
A fundamental question in biology is the following: what is the time scale that is needed for evolutionary innovations? There are many results that characterize single steps in terms of the fixation time of new mutants arising in populations of certain size and structure.
Chatterjee, Krishnendu   +3 more
openaire   +7 more sources

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

OPTICAL TIME SCALE

open access: yesLe Journal de Physique Colloques, 1981
The production of a time scale based on the use of an oscillation period of a highly stable laser is first reported. The new time standard allows to transfer frequency characteristics of a highly stable laser in the frequency range from 0 to 1014 Hz with no losses in accuracy.
openaire   +2 more sources

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Of Scales and Times

open access: yes21: Inquiries into Art, History, and the Visual
21: Inquiries into Art, History, and the Visual, Bd. 5 Nr. 1 (2024): 21: Inquiries into Art, History, and the Visual.
openaire   +2 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Nonlinear triple-point problems on time scales

open access: yesElectronic Journal of Differential Equations, 2004
We establish the existence of multiple positive solutions to the nonlinear second-order triple-point boundary-value problem on time scales, $$displaylines{ u^{Delta abla}(t)+h(t)f(t,u(t))=0, cr u(a)=alpha u(b)+delta u^Delta(a),quad eta u(c)+gamma u^Delta(
Douglas R. Anderson
doaj  

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