Results 141 to 150 of about 3,433,600 (309)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

A time series causal model [PDF]

open access: yes
Cause-effect relations are central in economic analysis. Uncovering empirical cause-effect relations is one of the main research activities of empirical economics.
Chen, Pu
core   +1 more source

On Time Reversibility of Linear Time Series

open access: yesJournal of Mathematical Extension, 2012
In this paper we suggest a procedure for testing reversibility of time series. Our approach is based on a necessary and sufficient condition for time reversibility of linear models. An attractive feature of the procedure is that in converse with other
M. Sharifdoust, S. Mahmoodi
doaj  

Beyond Information Distortion: Imaging Variable-Length Time Series Data for Classification

open access: yesSensors
Time series data are prevalent in diverse fields such as manufacturing and sensor-based human activity recognition. In real-world applications, these data are often collected with variable sample lengths, which can pose challenges for classification ...
Hyeonsu Lee, Dongmin Shin
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Exploring ICA for time series decomposition [PDF]

open access: yes
In this paper, we apply independent component analysis (ICA) for prediction and signal extraction in multivariate time series data. We compare the performance of three different ICA procedures, JADE, SOBI, and FOTBI that estimate the components ...
Ester González Prieto   +2 more
core  

Interpreting Economic Time Series

open access: yesJournal of Political Economy, 1980
This paper explores some of the implications for econometric practice of the principle that people's observed behavior will change when their constraints change. In dynamic contexts, a proper definition of people's constraints includes among them laws of motion that describe the evolution of the taxes they must pay and the prices of the goods that they
openaire   +3 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Terrain-Identification-from-Time-Series-Data [PDF]

open access: yes
Terrain Identification from Time Series Data. Public copy of my NCSU class repo at: https://github.ncsu.edu/kajadhav/Terrain-Identification-from-Time-Series-DataIf you use this software, please cite it as ...
Jadhav, Kaushik
core   +1 more source

Deep Learning for Anomaly Detection in Time-Series Data: An Analysis of Techniques, Review of Applications, and Guidelines for Future Research

open access: yesIEEE Access
Industries are generating massive amounts of data due to increased automation and interconnectedness. As data from various sources becomes more available, the extraction of relevant information becomes crucial for understanding complex systems’ ...
Usman Ahmad Usmani   +3 more
doaj   +1 more source

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