Results 121 to 130 of about 5,763,393 (289)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
High-Precision Single-Photon Laser Time Transfer with Temperature Drift Post-Compensation. [PDF]
Sensors (Basel), 2020 Meng W +7 more
europepmc +1 more source
Time–frequency transfer over optical fiber
National Science ReviewABSTRACT Optical time–frequency transfer establishes the metrological linkage in large-scale clock networks, which facilitates various applications. Fiber-based transfer benefits from the abundant deployment of fiber infrastructures to achieve this advantage.
Ziyang Chen +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Time Division Wireless Power Transfer Using Receiver Grouping
IEEE AccessWireless power transfer (WPT) has attracted significant attention as a method of supplying energy to low-power devices, such as Internet of Things (IoT) and sensor devices.
Yuna Sawada +5 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Research of Eliminating the Day-Boundary Discontinuities in GNSS Carrier Phase Time Transfer through Network Processing. [PDF]
Sensors (Basel), 2020 Zhang X, Guo J, Hu Y, Zhao D, He Z.
europepmc +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
High-Precision Time Transfer and Relative Orbital Determination Among LEO Satellites in Real Time
NavigationFor low-Earth-orbit (LEO) satellites, high-precision clock estimation often depends on high-precision real-time global navigation satellite system (GNSS) products. Thus, service providers often choose to downlink observation data to the ground to achieve
Kan Wang +3 more
doaj +1 more source