Results 181 to 190 of about 627,123 (359)

Comparing absolute and relative distance and time travel measures of geographic access to healthcare facilities in rural Haiti. [PDF]

BMJ Open, 2022
Bhangdia KP, Iyer HS, Joseph JP, Dorne RL, Mukherjee J, Fadelu T.   +5 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

The role of temporal distance of the events on the spatiotemporal dynamics of mental time travel to one's personal past and future. [PDF]

Sci Rep, 2022
Colás-Blanco I, Mioche J, La Corte V, Piolino P.   +3 more
europepmc   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source

An asymmetry in past and future mental time travel following vmPFC damage. [PDF]

Soc Cogn Affect Neurosci, 2021
Ciaramelli E, Anelli F, Frassinetti F.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Uncovering the Distribution of Motorists' Preferences for Travel Time and Reliability

We apply recent econometric advances to study the distribution of commuters' preferences for speedy and reliable highway travel. Our analysis applies mixed logit to combined revealed and stated preference data on commuter choices of whether to pay a toll
Winston, Clifford, Yan, Jia, Small, Kenneth A.   +2 more
core  

Travel cost and time measurement in travel cost models. [PDF]

Cost; Measurement; Model; Models; Time; Working;
Proost, Stef, Eggermont, K, Hermy, Martin, Moons, Ellen, Loomis, J   +4 more
core  

Exploring Spatiotemporal Accessibility of Urban Fire Services Using Real-Time Travel Time. [PDF]

Int J Environ Res Public Health, 2021
Chen Y, Li Y, Wu G, Zhang F, Zhu K, Xia Z, Chen Y.   +6 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source