Results 71 to 80 of about 2,785,336 (285)
Impact of Locally Suppressed Wave sources on helioseismic travel times
, 2008 Wave travel-time shifts in the vicinity of sunspots are typically interpreted as arising predominantly from magnetic fields, flows, and local changes in sound speed.
A. C. Birch +43 more
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Optimal time travel in the Godel universe
, 2011 Using the theory of optimal rocket trajectories in general relativity, recently developed in arXiv:1105.5235, we present a candidate for the minimum total integrated acceleration closed timelike curve in the Godel universe, and give evidence for its ...
C. Misner +13 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The value of business travel time savings [PDF]
, 1986 The value of time savings for business travellers forms a sizeable part of the benefits from trunk road, rail and air transport improvement schemes.
Fowkes, A.S., Marks, P., Nash, C.A.
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Time Travelers (and Everyone Else) Cannot Do Otherwise
PhilosophiesMany defenders of the possibility of time travel into the past also hold that such time travel places no restrictions on what said time travelers can do. Some hold that it places at least a few restrictions on what time travelers can do. In attempting to
G. C. Goddu
doaj +1 more source
Travel Time Shifts due to Amplitude Modulation in Time-Distance Helioseismology
, 2009 Correct interpretation of acoustic travel times measured by time-distance helioseismology is essential to get an accurate understanding of the solar properties that are inferred from them. It has long been observed that sunspots suppress p-mode amplitude,
A. G. Kosovichev +9 more
core +1 more source