Results 81 to 90 of about 234,786 (282)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Determinan Audit Delay dan Timeliness

open access: yesJurnal Riset dan Aplikasi: Akuntansi dan Manajemen, 2015
Timeliness of drafting or reporting an audit report on the company's financial statements could affect the value of such financial statements. If financial statement information is not delivered in a timely manner, thus it is not relevant which could ...
Oyong Lisa
doaj  

Routine vaccination coverage of children aged 1-7 years in Zhejiang province, China

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Background: This study was to evaluate the coverage, completeness and timeliness of routine vaccination among children aged 1–7 years in Zhejiang province.
Yu Hu, Yaping Chen, Hui Liang, Ying Wang
doaj   +1 more source

Timeliness of Surveillance during Outbreak of Shiga Toxin–producing Escherichia coli Infection, Germany, 2011

open access: yesEmerging Infectious Diseases, 2011
In the context of a large outbreak of Shiga toxin–producing Escherichia coli O104:H4 in Germany, we quantified the timeliness of the German surveillance system for hemolytic uremic syndrome and Shiga toxin–producing E.
Mathias Altmann   +7 more
doaj   +1 more source

Teaching and Assessing Soft Skills [PDF]

open access: yes, 2018
[excerpt from article] It is our job as legal educators to put our law graduates in the best position to succeed as new lawyers.1 And to succeed, law graduates must possess certain qualities or character traits that will enable them to thrive within ...
Sparrow, Sophie M.
core   +2 more sources

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Timeliness Study of Home Energy Management System Based on Dynamic Allocation of Bandwidth

open access: yesIEEE Access
Household electrical appliances have developed into a significant part of demand response as a result of the widespread use of smart meters and the popularity of home energy management systems.
Wei Zhang, Chenhao Huang
doaj   +1 more source

Approximation of δ-Timeliness [PDF]

open access: yes, 2010
In asynchronous message-passing distributed systems prone to process crashes, a communication link is said δ-timely if the communication delay on this link is bounded by some constant δ. We study here in which way processes may approximate and find structural properties based on δ-timeliness (e.g., find δ-timely paths between processes or build a ring ...
Carole Delporte-Gallet   +2 more
openaire   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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