Results 191 to 200 of about 28,704 (262)
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Drugs & Aging, 2006
Travoprost 0.004%/timolol 0.5% fixed combination (travoprost/timolol) is a once-daily eyedrops solution comprising the prostaglandin F(2alpha) analogue travoprost and the beta-adrenoceptor antagonist timolol. It is indicated for the treatment of patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to topical beta ...
Sheridan M, Hoy +2 more
openaire +2 more sources
Travoprost 0.004%/timolol 0.5% fixed combination (travoprost/timolol) is a once-daily eyedrops solution comprising the prostaglandin F(2alpha) analogue travoprost and the beta-adrenoceptor antagonist timolol. It is indicated for the treatment of patients with open-angle glaucoma or ocular hypertension who are insufficiently responsive to topical beta ...
Sheridan M, Hoy +2 more
openaire +2 more sources
Cutaneous and Ocular Toxicology, 2020
Purpose The objective of this study was to investigate the influence of topical preservative-free timolol, benzalkonium chloride(BAC)-preserved timolol, BAC-preserved timolol, and BAC-preserved brimonidine on total protein concentration, advanced ...
L. Sedlak +3 more
semanticscholar +1 more source
Purpose The objective of this study was to investigate the influence of topical preservative-free timolol, benzalkonium chloride(BAC)-preserved timolol, BAC-preserved timolol, and BAC-preserved brimonidine on total protein concentration, advanced ...
L. Sedlak +3 more
semanticscholar +1 more source
Journal of Controlled Release, 2019
Glaucoma is a group of irreversible ocular diseases which result in damage to the optic nerve and vision loss. The objective of the present work was to develop micelles-laden contact lenses (CLs-M) that could achieve the sustained release of timolol and ...
Jiawen Xu +10 more
semanticscholar +1 more source
Glaucoma is a group of irreversible ocular diseases which result in damage to the optic nerve and vision loss. The objective of the present work was to develop micelles-laden contact lenses (CLs-M) that could achieve the sustained release of timolol and ...
Jiawen Xu +10 more
semanticscholar +1 more source
Acta Biomaterialia, 2019
Contact lenses are ideally suited for extended drug delivery to the ocular tissues, but incorporation of any particulate system affects the critical properties of the contact lens. Timolol loading by the conventional soaking method does not significantly
Furqan A. Maulvi +8 more
semanticscholar +1 more source
Contact lenses are ideally suited for extended drug delivery to the ocular tissues, but incorporation of any particulate system affects the critical properties of the contact lens. Timolol loading by the conventional soaking method does not significantly
Furqan A. Maulvi +8 more
semanticscholar +1 more source
, 2020
To manage glaucoma, timolol is currently delivered via eye drop solution in high doses due to poor ocular bioavailability. The silicone contact lenses can be used to control the release of timolol by conventional soaking technology without changing or ...
Ning Wei +3 more
semanticscholar +1 more source
To manage glaucoma, timolol is currently delivered via eye drop solution in high doses due to poor ocular bioavailability. The silicone contact lenses can be used to control the release of timolol by conventional soaking technology without changing or ...
Ning Wei +3 more
semanticscholar +1 more source
International journal of pharmaceutics, 2019
Glaucoma treatment with ocular medications requires overcoming the corneal barrier to drug penetration. Liposomes have a great corneal penetration ability and affinity while suffering from poor stability and low entrapment of hydrophilic drugs ...
R. Hathout +9 more
semanticscholar +1 more source
Glaucoma treatment with ocular medications requires overcoming the corneal barrier to drug penetration. Liposomes have a great corneal penetration ability and affinity while suffering from poor stability and low entrapment of hydrophilic drugs ...
R. Hathout +9 more
semanticscholar +1 more source
International journal of pharmaceutics, 2018
The use of gelatin has been gaining recognition in ocular delivery for its safety profile and biocompatible properties. Timolol Maleate (TM) is an anti‐glaucoma drug possessing poor corneal penetration while causing eye irritation making it an ideal ...
Miral Shokry, R. Hathout, S. Mansour
semanticscholar +1 more source
The use of gelatin has been gaining recognition in ocular delivery for its safety profile and biocompatible properties. Timolol Maleate (TM) is an anti‐glaucoma drug possessing poor corneal penetration while causing eye irritation making it an ideal ...
Miral Shokry, R. Hathout, S. Mansour
semanticscholar +1 more source
Topical timolol as adjunct therapy to shorten oral propranolol therapy for infantile hemangiomas
Pediatric dermatology, 2019First‐line therapy for infantile hemangiomas (IH) is oral propranolol, a systemic beta‐blocker with the risk of rare but serious adverse effects. Topical timolol presents an attractive off‐label alternative with good tolerability, but sequential therapy ...
D. Mannschreck +4 more
semanticscholar +1 more source
Journal of Pharmacy and Science, 2018
Ocular hypertension due to increased intraocular pressure is a major risk factor for the development of glaucoma. Rapid clearance and low ocular bioavailability are drawbacks of conventional ocular treatments.
Gina S. El-Feky +3 more
semanticscholar +1 more source
Ocular hypertension due to increased intraocular pressure is a major risk factor for the development of glaucoma. Rapid clearance and low ocular bioavailability are drawbacks of conventional ocular treatments.
Gina S. El-Feky +3 more
semanticscholar +1 more source