Results 71 to 80 of about 4,356 (97)
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Frequency of Timolol Administration
American Journal of Ophthalmology, 1981We treated 20 patients who had primary open-angle glaucoma with either 0.25% or 0.5% timolol for nine weeks. Once-daily administration of timolol significantly reduced intraocular pressure (to less than 21 mm Hg) in nine patients; four patients required twice-daily administration. In seven cases, we judged the treatment to have failed.
Leonard Rothkoff +4 more
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2007
Timolol is a non-selective, beta adrenoceptor antagonist at beta-1 and beta-2 adrenoceptors. It lacks the partial agonist and local anesthetic properties that some drugs in this class have. It is most commonly used to treat glaucoma and cardiovascular diseases. Timolol is moderately lipophilic. Absorption of timolol after topical application to the eye
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Timolol is a non-selective, beta adrenoceptor antagonist at beta-1 and beta-2 adrenoceptors. It lacks the partial agonist and local anesthetic properties that some drugs in this class have. It is most commonly used to treat glaucoma and cardiovascular diseases. Timolol is moderately lipophilic. Absorption of timolol after topical application to the eye
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Ophthalmology, 1979
Data from clinical records of patients using timolol confirm the ocular hypotensive effect of the drug in secondary glaucoma, aphakic glaucoma, ocular hypertension, and when used in combination with various other forms of glaucoma therapy. No serious local or systemic side effects were noted.
Thom J. Zimmerman, Pamela Canale
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Data from clinical records of patients using timolol confirm the ocular hypotensive effect of the drug in secondary glaucoma, aphakic glaucoma, ocular hypertension, and when used in combination with various other forms of glaucoma therapy. No serious local or systemic side effects were noted.
Thom J. Zimmerman, Pamela Canale
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Acta Ophthalmologica, 1980
Thirty‐eight patients with ocular hypertension or glaucoma were treated with topical timolol for 12–30 months (mean 20). A long lasting hypotensive effect of timolol eyedrops was found. However a need to increase therapy during the follow‐up period was noted especially in the glaucoma group.
N. Marén, Berit Calissendorff
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Thirty‐eight patients with ocular hypertension or glaucoma were treated with topical timolol for 12–30 months (mean 20). A long lasting hypotensive effect of timolol eyedrops was found. However a need to increase therapy during the follow‐up period was noted especially in the glaucoma group.
N. Marén, Berit Calissendorff
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Archives of Ophthalmology, 1984
To the Editor. —The article comparing efficacy and side effects of betaxolol and timolol in lowering intraocular pressures by Berry et al 1 in the JanuaryArchivesraises several interesting points. The comparison between the two drugs was not conducted on a random sample of eyes with elevated IOP.
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To the Editor. —The article comparing efficacy and side effects of betaxolol and timolol in lowering intraocular pressures by Berry et al 1 in the JanuaryArchivesraises several interesting points. The comparison between the two drugs was not conducted on a random sample of eyes with elevated IOP.
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Timolol-Pilocarpine Combined vs Timolol and Pilocarpine Given Separately
American Journal of Ophthalmology, 1989In a controlled, double-observer, multicenter study, we compared the effect of a fixed combination of timolol 0.5%-pilocarpine 4% twice a day with that of timolol 0.5% twice a day plus pilocarpine 4% three times a day in 80 patients with open-angle glaucoma whose intraocular pressure was greater than 21 mm Hg on timolol 0.5% twice a day alone ...
örjan Wallin +3 more
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Ocular and cardiac β-antagonism by timolol prodrugs, timolol and levobunolol
Current Eye Research, 1988Topically applied O-butyryl timolol, O-pivaloyl timolol and levobunolol (0.25 micrograms) antagonized isoproterenol-induced ocular hypotension for 8 hrs whereas timolol (0.25 micrograms) was shorter acting (4 hrs). Timolol (25 micrograms) produced greater antagonism of isoproterenol-induced tachycardia than did O-butyryl and O-pivaloyl timolol (25 ...
Vincent H.L. Lee +3 more
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Travoprost/timolol fixed combination
Expert Opinion on Pharmacotherapy, 2008Travoprost and timolol are topical ocular hypotensive medications that have been used in the treatment of glaucoma. The fixed combination eye drop, Duotrav (travoprost 0.004% and timolol maleate 0.5%), has recently been introduced into the market.In this paper, the results of clinical trials and existing data on the performance of travoprost/timolol ...
Michael Herceg, Robert J. Noecker
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Plasma Timolol in glaucoma Patients
Ophthalmology, 1984Plasma timolol levels were measured in our timolol-treated glaucoma patients employing three protocols: (1) measurements in ten patients over age 60 on chronic timolol therapy before, one hour, and three hours after receiving one drop of 0.5% timolol, (2) measurements in nine adult patients, with and without punctal occlusion, and (3) random ...
Earl A. Palmer +2 more
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Cardiac safety of ophthalmic timolol
Expert Opinion on Drug Safety, 2016It is generally believed that topical administration of eye drops safeguards against harmful systemic effects. However, about 80% of the drug in the ophthalmic products is systemically absorbed and the first-pass metabolism is avoided. Ophthalmic timolol is widely prescribed in the treatment of glaucoma either alone or in the combination eye drop ...
Jukka Mäenpää, Olavi Pelkonen
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