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Vestnik oftal'mologii, 2019
In recent years, β-adrenergic blockers have become the first choice drugs for glaucoma treatment. Timolol holds the main position among them, being a part of most combined antiglaucoma preparations. The use of timolol maleate in clinical practice may be accompanied by severe side effects affecting different organs and systems.
L K, Moshetova +3 more
openaire +2 more sources
In recent years, β-adrenergic blockers have become the first choice drugs for glaucoma treatment. Timolol holds the main position among them, being a part of most combined antiglaucoma preparations. The use of timolol maleate in clinical practice may be accompanied by severe side effects affecting different organs and systems.
L K, Moshetova +3 more
openaire +2 more sources
Acta Ophthalmologica, 1986
Abstract The influence of timolol on the corneal epithelium and endothelium was studied in organ culture. The cell morphology was not influenced by drug concentrations ≦ 690 μg/ml. Cell death was observed at 6900 μg/ml. Endothelial cell proliferation after an experimental injury was slowed down at a drug concentration of 690 μg/ml.
E G, Olsen, M, Davanger
openaire +2 more sources
Abstract The influence of timolol on the corneal epithelium and endothelium was studied in organ culture. The cell morphology was not influenced by drug concentrations ≦ 690 μg/ml. Cell death was observed at 6900 μg/ml. Endothelial cell proliferation after an experimental injury was slowed down at a drug concentration of 690 μg/ml.
E G, Olsen, M, Davanger
openaire +2 more sources
2007
Timolol is a non-selective, beta adrenoceptor antagonist at beta-1 and beta-2 adrenoceptors. It lacks the partial agonist and local anesthetic properties that some drugs in this class have. It is most commonly used to treat glaucoma and cardiovascular diseases. Timolol is moderately lipophilic. Absorption of timolol after topical application to the eye
openaire +2 more sources
Timolol is a non-selective, beta adrenoceptor antagonist at beta-1 and beta-2 adrenoceptors. It lacks the partial agonist and local anesthetic properties that some drugs in this class have. It is most commonly used to treat glaucoma and cardiovascular diseases. Timolol is moderately lipophilic. Absorption of timolol after topical application to the eye
openaire +2 more sources