Results 151 to 160 of about 23,531 (251)

ApoE‐ and Cfh‐deficient mice exhibit structural and molecular features of human early–intermediate retinal degeneration

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Age‐related macular degeneration (AMD) involves lipid dysregulation and complement overactivation. Here, we characterize a double‐knockout ApoE−/−/Cfh−/− mouse as a model of early–intermediate retinal degeneration. These mice exhibit retinal pigment epithelium thinning, Bruch's membrane thickening, lipid accumulation, enhanced C5b‐9 deposition ...
Sergio Recalde   +9 more
wiley   +1 more source

Tunable Regional Targeting of Self‐Assembling Peptide Nanomaterials in Acute Myocardial Infarction

open access: yesAdvanced NanoBiomed Research, EarlyView.
In a rat model of acute myocardial infarction, intravascular delivery of peptide nanofibers with a collagen‐targeting peptide bound to the infarct vasculature while globular peptide nanoparticles penetrated into the infarct area. This study demonstrated that size, shape, and surface chemistry of nanomaterials control the delivery location within the ...
Alexander Chen   +14 more
wiley   +1 more source

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

open access: yesAdvanced NanoBiomed Research, EarlyView.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei   +2 more
wiley   +1 more source

Molecular Dioxygen‐Mediated Passivation of Electron Traps in n‐Type Organic Charge‐Transfer Complexes

open access: yesAngewandte Chemie International Edition, EarlyView.
O2 enhances charge‐transfer in n‐type organic donor–acceptor charge‐transfer complexes (CTCs) via physisorption‐mediated trap passivation. By suppressing recombination and promoting long‐lived delocalized charge carriers, O2 improves electron transport and conductivity without doping.
Kirill K. Gubanov   +16 more
wiley   +1 more source

Surface Charges Guided Quasi‐TEM‐mode Microwave Propagation along Dielectric Nanowire

open access: yesAdvanced Physics Research, EarlyView.
According to Maxwell's equations, a single‐conductor transmission line cannot allow TEM‐mode electromagnetic wave propagation, however, this is based upon the assumption that dielectric material is isolated from the environment. In practice, surface electrostatic charges widely existed in nano‐materials with large surface‐to‐volume ratio.
BoYan Xu   +7 more
wiley   +1 more source

Guiding and Manipulating Light Fields in Microstructured Liquid Crystals

open access: yesAdvanced Physics Research, EarlyView.
This review summarizes recent advances in guided‐wave optics enabled by microstructured liquid crystal (LC) devices, covering their fundamental material properties, key degree of freedom for dynamic light field manipulations. The advances of linear guided‐wave optics, nonlinear‐optics with spatial optical solitons, and microlasers in LC‐based devices ...
Shan‐shan Chang   +2 more
wiley   +1 more source

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