Results 31 to 40 of about 976,747 (247)

Prediction of Blade Tip Timing Sensor Waveforms Based on Radial Basis Function Neural Network

open access: yesApplied Sciences, 2023
As the existing Blade Tip Timing (BTT) vibration measurement methods have serious under-sampling problems, where the blade resonance frequency is usually higher than the sampling frequency of the data acquisition system of the BTT method, resulting in ...
Liang Zhang   +4 more
doaj   +1 more source

Blade Crack Diagnosis Based on Blade Tip Timing and Convolution Neural Networks

open access: yesApplied Sciences, 2023
The diagnosis of blade crack faults is critical to ensuring the safety of turbomachinery. Blade tip timing (BTT) is a non-contact vibration displacement measurement technique, which has been extensively studied for blade vibration condition monitoring ...
Guangya Zhu   +5 more
doaj   +1 more source

Positive Feedback Defines the Timing, Magnitude, and Robustness of Angiogenesis

open access: yesCell Reports, 2019
Summary: Angiogenesis is driven by the coordinated collective branching of specialized leading “tip” and trailing “stalk” endothelial cells (ECs). While Notch-regulated negative feedback suppresses excessive tip selection, roles for positive feedback in ...
Donna J. Page   +5 more
doaj   +1 more source

A Class of Methods for the Analysis of Blade Tip Timing Data from Bladed Assemblies Undergoing Simultaneous Resonances—Part II: Experimental Validation

open access: yesInternational Journal of Rotating Machinery, 2007
Blade tip timing is a technique for the measurement of vibrations in rotating bladed assemblies. In Part I of this work a class of methods for the analysis of blade tip timing data from bladed assemblies undergoing two simultaneous synchronous resonances
J. Gallego-Garrido   +3 more
doaj   +1 more source

A Study on the High Load Operation of a Natural Gas-Diesel Dual-Fuel Engine

open access: yesFrontiers in Mechanical Engineering, 2020
Diesel fueled compression ignition engines are widely used in power generation and freight transport owing to their high fuel conversion efficiency and ability to operate reliably for long periods of time at high loads.
Shouvik Dev, Hongsheng Guo, Brian Liko
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Design and Uncertainty Evaluation of a Calibration Setup for Turbine Blades Vibration Measurement

open access: yesSensors
Turbomachinery engines face significant failure risks due to the combination of thermal loads and high-amplitude vibrations in turbine and compressor blades.
Lorenzo Capponi   +8 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

A Class of Methods for the Analysis of Blade Tip Timing Data from Bladed Assemblies Undergoing Simultaneous Resonances—Part I: Theoretical Development

open access: yesInternational Journal of Rotating Machinery, 2007
Blade tip timing is a technique for the measurement of vibrations in rotating bladed assemblies. Although the fundamentals of the technique are simple, the analysis of data obtained in the presence of simultaneously occurring synchronous resonances is ...
J. Gallego-Garrido   +2 more
doaj   +1 more source

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