Results 31 to 40 of about 71,632 (231)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
A Study on the High Load Operation of a Natural Gas-Diesel Dual-Fuel Engine
Frontiers in Mechanical Engineering, 2020 Diesel fueled compression ignition engines are widely used in power generation and freight transport owing to their high fuel conversion efficiency and ability to operate reliably for long periods of time at high loads.
Shouvik Dev, Hongsheng Guo, Brian Liko
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Design and Uncertainty Evaluation of a Calibration Setup for Turbine Blades Vibration Measurement
SensorsTurbomachinery engines face significant failure risks due to the combination of thermal loads and high-amplitude vibrations in turbine and compressor blades.
Lorenzo Capponi +8 more
doaj +1 more source
Analysis and Calibration of Blade Tip-Timing Vibration Measurement Under Variable Rotating Speeds
IEEE Access, 2021 Blade tip timing (BTT) vibration measurement is a promising on-line blade monitoring method, but various uncertainties bring great challenge in engineering applications. Most existing works are based on the assumption of constant rotating speeds. However,
Zhongsheng Chen +3 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
International Journal of Rotating Machinery, 2007 Blade tip timing is a technique for the measurement of vibrations in rotating bladed assemblies. Although the fundamentals of the technique are simple, the analysis of data obtained in the presence of simultaneously occurring synchronous resonances is ...
J. Gallego-Garrido +2 more
doaj +1 more source
CNN-based defect diagnosis method for rotating blades
You-qi chuyun, 2020 In order to solve the problem of difficult blade defect diagnosis caused by severe signal under-sampling in tiptiming technology, a defect diagnosis method for rotating blade based on convolution neural network (CNN) was proposed.In the method, the under-
Jiwang ZHANG +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
A Torsional Vibration Measurement Method for Rotating Blades Based on Blade Tip Timing
Shock and Vibration, 2021 During the working process of the turbine, some types of faults can cause changes in the vibration characteristics of the blades. The real-time vibration monitoring of the blades is of great significance to the stable operation and state-based ...
Haonan Guo +6 more
doaj +1 more source