Results 21 to 30 of about 2,271,076 (186)

Tipping points in neurodegeneration

open access: yesNeuron, 2023
In Alzheimer's disease (AD), Aβ deposits form slowly, several decades before further pathological events trigger neurodegeneration and dementia. However, a substantial proportion of affected individuals remains non-demented despite AD pathology, raising questions about the underlying factors that determine the transition to clinical disease.
Simons, Mikael   +2 more
openaire   +5 more sources

High probability of triggering climate tipping points under current policies modestly amplified by Amazon dieback and permafrost thaw [PDF]

open access: yesEarth System Dynamics
We investigate the probabilities of triggering climate tipping points under five Shared Socioeconomic Pathways (SSPs) and how they are altered by including the additional carbon emissions that could arise from tipping points within the Earth's carbon ...
J. Deutloff   +4 more
doaj   +1 more source

Perspectives on tipping points in integrated models of the natural and human Earth system: cascading effects and telecoupling

open access: yesEnvironmental Research Letters, 2022
The Earth system and the human system are intrinsically linked. Anthropogenic greenhouse gas emissions have led to the climate crisis, which is causing unprecedented extreme events and could trigger Earth system tipping elements.
Christian L E Franzke   +8 more
doaj   +1 more source

Ambiguous Tipping Points [PDF]

open access: yesSSRN Electronic Journal, 2015
We analyze the policy implications of aversion to Knightian uncertainty (ambiguity) about the possibility of tipping points. We demonstrate two channels through which uncertainty aversion affects optimal policy in the general setting. The first channel relates to the policy's effect on the probability of tipping, and the second channel to its ...
Derek Lemoine, Christian P. Traeger
openaire   +1 more source

The commercial tipping point [PDF]

open access: yesNature Biotechnology, 2017
RNA-based therapeutics are poised to become successful commercial products, but wide adoption across the biopharmaceutical industry will likely take a few more years.
Brady, Huggett, Kathryn, Paisner
openaire   +2 more sources

Socio-metabolic risk and tipping points on islands

open access: yesEnvironmental Research Letters, 2022
Small Island Developing States (SIDS) face enormous sustainability challenges such as heavy reliance on imports to meet basic needs, tenuous resource availability, coastal squeeze, and reduced waste absorption capacity.
Simron J Singh   +6 more
doaj   +1 more source

The Economics of Tipping Points [PDF]

open access: yesEnvironmental and Resource Economics, 2016
The Beijer Institute organizes workshops for economists and ecologists to meet, to talk to each other, and to work together. At one of these workshops in Gozo, Malta, in 1998, the ecologists Stephen Carpenter and Marten Scheffer presented their shallow lake model.
de Zeeuw, Aart, Li, Chuang-Zhong
openaire   +2 more sources

Missing the (tipping) point: the effect of information about climate tipping points on public risk perceptions in Norway [PDF]

open access: yesEarth System Dynamics
Climate tipping points are a topic of growing interest in climate research and a frequent communication tool in the media to warn of dangerous climate change.
C. Nadeau   +3 more
doaj   +1 more source

The Tipping Points of Technology Development

open access: yesKvalita Inovácia Prosperita, 2014
The tipping point, the decisive point in time in the competition between old and new, is an interesting phenomenon in physics of today. This aspect in technology acceptance is connected to many business decisions such as technology investments, product ...
Tauno Kekäle, Petri Helo
doaj   +1 more source

Amazon Tipping Point [PDF]

open access: yesScience Advances, 2018
Thomas E. Lovejoy Carlos Nobre In the 1970s, Brazilian scientist Eneas Salati shattered the long held dogma that vegetation is simply the consequence of climate and has no influence on climate whatsoever ( 1 ). Using isotopic ratios of oxygen in rainwater samples collected from the Atlantic to the Peruvian border, he was able to demonstrate ...
Lovejoy, Thomas E., Nobre, Carlos
openaire   +2 more sources

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