Results 61 to 70 of about 172,142 (304)

Synthesis and characterization of ultra-soft alginate hydrogel mimicking lung tissue

International Journal of Smart and Nano Materials
Alginate hydrogels possess properties analogous to those of the extracellular matrix (ECM). Thus, their mechanical behavior approximates soft tissue, which makes them desirable for the production of tissue-equivalent soft deformable structures.
Xiangpeng Li, Jihua Gou, Chiranjit Maiti, Olusegun J. Ilegbusi   +3 more
doaj   +1 more source

Antimicrobial efficacy against Pseudomonas aeruginosa biofilm formation in a three-dimensional lung epithelial model and the influence of fetal bovine serum [PDF]

, 2017
In vitro models that mimic in vivo host-pathogen interactions are needed to evaluate candidate drugs that inhibit bacterial virulence traits. We established a new approach to study Pseudomonas aeruginosa biofilm susceptibility on biotic surfaces, using a
Coenye, Tom, Crabbé, Aurélie, Davis, Richard, De La Fuente-Nùñez, César, Hancock, Robert EW, Ledesma, Maria A, Liu, Yulong, Matthijs, Nele, Nickerson, Cheryl A., Rigole, Petra, Sarker, Shameema, Van Houdt, Rob   +11 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Development and investigation of skin melanoma phantoms for ultrasonic examination

Acta Medica Lituanica, 2013
Background. The purpose of this study was to develop skin mimicking phantoms with melanoma-like insertion with acoustic properties similar to the human skin.
Kristina Andrėkutė, Ilona Subotinaitė, Skaidra Valiukevičienė, Renaldas Raišutis   +3 more
doaj   +1 more source

MicroRNAs delivery into human cells grown on 3D-printed PLA scaffolds coated with a novel fluorescent PAMAM dendrimer for biomedical applications [PDF]

, 2018
Many advanced synthetic, natural, degradable or non-degradable materials have been employed to create scaffolds for cell culture for biomedical or tissue engineering applications. One of the most versatile material is poly-lactide (PLA), commonly used as
Abbaszadeh, Zeinab, D'Oria, Valentina, Dalla Cort, Antonella, Giannicchi, Ilaria, Leoni, Luca, Masotti, Andrea, Mura, Francesco, Paolini, Alessandro   +7 more
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Development of a measurement setup to determine the frictional properties of tissuemimicking materials for vascular models

Current Directions in Biomedical Engineering
In this study, a measurement setup was developed to determine the frictional properties between tissue-mimicking and implant materials. Nitinol and Polytetrafluoroethylene (PTFE) were selected as implant materials, while Polyvinyl alcohol (PVA) hydrogel ...
Karcher Alisa, Schäfer Jenny, Cattaneo Giorgio, Sanchez Daniela   +3 more
doaj   +1 more source

Computed Tomography Attenuation of Three-Dimensional (3D) Printing Materials—Depository to Aid in Constructing 3D-Printed Phantoms

Micromachines, 2023
Three-dimensionally printed phantoms are increasingly used in medical imaging and research due to their cost-effectiveness and customizability, offering valuable alternatives to commercial phantoms.
Yuktesh Kalidindi, Aravinda Krishna Ganapathy, Yash Nayak, Anusha Elumalai, David Z. Chen, Grace Bishop, Adrian Sanchez, Brian Albers, Anup S. Shetty, David H. Ballard   +9 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Providing adhesion for a miniture mobile intra-abdominal device based on biomimetic principles [PDF]

, 2009
This paper investigates the surface adhesion characteristics required for a miniature mobile device to move around the abdominal cavity. Such a device must be capable of adhering to the tissue lining and move freely across the upper surface of the ...
Gaskell, P.H., Jayne, D., Liskiewicz, T., Morina, A., Neville, A., Taylor, G.   +5 more
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