Results 141 to 150 of about 4,737,680 (328)

In vivo measurement of afferent activity with axon-specific calcium imaging. [PDF]

, 2018
In vivo calcium imaging from axons provides direct interrogation of afferent neural activity, informing the neural representations that a local circuit receives.
Broussard, Gerard Joey, Fridman, Marina, Ji, Na, Liang, Yajie, Meng, Guanghan, Petreanu, Leopoldo, Tian, Lin, Unger, Elizabeth K, Xiao, Xian   +8 more
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Fibrin glue in ophthalmology

Indian Journal of Ophthalmology, 2009
Suturing is a time consuming task in ophthalmology and suture induced irritation and redness are frequent problems. Postoperative wound infection and corneal graft rejection are examples of possible suture related complications.
Panda Anita, Kumar Sandeep, Kumar Abhiyan, Bansal Raseena, Bhartiya Shibal   +4 more
doaj  

Percutaneous transhepatic obliteration with N-butyl-2-cyanoacrylate in a patient with a superior mesenteric vein intraluminal distal small bowel variceal bleed

International Journal of Gastrointestinal Intervention
Gastrointestinal (GI) bleeding is a serious complication with a high mortality rate (45%-55%) that can result from a variety of conditions, including portal hypertension, diverticulosis, or splenic vein thrombosis.
William Henry Eskew, Jesus Beltran-Perez, Bruce Bordlee   +2 more
doaj   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Allergic reactions from tissue adhesives in spine surgery: a sticky situation. [PDF]

J Spine Surg, 2023
Wellington IJ, Antonacci CL, Mancini MR, Moss IL.   +3 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

A pH-driven genipin gelator to engineer decellularized extracellular matrix-based tissue adhesives.

Acta Biomaterialia, 2021
A. Nishiguchi, T. Taguchi
semanticscholar   +1 more source

Your Turn, Doctor [PDF]

, 2017
Between incurably degenerative illness and the graffiti which ignited the Syrian Civil War, YOUR TURN, DOCTOR complicates hope. When myths of revolution, of wellness, no longer console—love as measured in anything but loss.
Mozayen, Leyla
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source