Results 131 to 140 of about 5,836,972 (287)

Thyroid doses for the Chornobyl Tissue Bank: improved estimates based on revised methodology and individual residence and diet history. [PDF]

Radiat Environ Biophys
Masiuk S, Chepurny M, Buderatska V, Ivanova O, Boiko Z, Zhadan N, Chornovol H, Bolgov M, Shpak V, Tronko M, Cahoon EK, Chanock SJ, Bogdanova T, Morton LM, Drozdovitch V.   +14 more
europepmc   +1 more source

HSP90AB1‐Mediated Ubiquitin‐Proteasome Degradation of ITGBL1 Promotes Osteosarcoma Progression by Inhibiting Endoplasmic Reticulum Stress‐Induced Autophagy

Advanced Science, EarlyView.
This study delineates a novel HSP90AB1‐ITGBL1 signaling axis governing osteosarcoma. HSP90AB1 promotes K63‐linked ubiquitination and proteasomal degradation of ITGBL1. Restoring ITGBL1 induces reactive oxygen species‐dependent endoplasmic reticulum stress and pro‐death autophagy, suppressing tumor growth and metastasis.
Zhen Wang, Zixuan Guo, Chengwei Cao, Ziying Wang, Zifu Huang, Xiujuan Zhang, Yushu Zheng, Diankun She, Hao Zhu, Lingfeng Yu, Xuelin Zhao, Dongquan Xiang, Song Liao, Xin He, Xintong Ji, Chengsheng Wu, Cheng‐Xiong Xu, Meng Xu   +17 more
wiley   +1 more source

Cardiovascular disease and adult healing cells: From bench top to bedside [PDF]

, 2017
Black Jr., Asa C, Black, Gypsy F., Coleman, Julie, Hawkins, Kristina C, Lachner, Frank, Limnios, Jason Ionnis, McCommon, George, Williams, Shanna, Young, Henry E.   +8 more
core   +1 more source

INDIVIDUAL THYROID DOSE ESTIMATES FOR THE GENOMIC STUDY OF FOLLICULAR CARCINOMAS AND ADENOMAS IN PARTICIPANTS OF THE CHORNOBYL TISSUE BANK. [PDF]

Probl Radiac Med Radiobiol
Masiuk SV, Chepurny MI, Buderatska VB, Ivanova OM, Boiko ZN, Zhadan NS, Chornovol HV, Bolgov MY, Shpak VM, Tronko MD, Bogdanova TI, Karyadi D, Vij V, Cahoon EK, Chanock SJ, Morton LM, Drozdovitch V.   +16 more
europepmc   +1 more source

Real‐Time Visualization of Isoform‐Specific RAF‐KRAS Interactions in Living Cells Using FRET‐BRET Hybrid Biosensors

Advanced Science, EarlyView.
Hybrid FRET–BRET biosensors were developed to monitor RAF–KRAS interactions in living cells. These sensors enable real‐time visualization of interaction dynamics, quantitative spectral analysis, and validation of mutation‐selective inhibitors, providing a versatile platform for probing KRAS regulation and therapeutic responses. ABSTRACT The RAS–RAF–MEK–
Jeong‐Min Go, Dahee Lee, Minji Kim, Kiseok Han, Gyuho Choi, ChanHui Song, Sanghyun Ahn, Yerim Lee, Jinyoung Lee, Yingxiao Wang, Jung‐Soo Suh, Hwayoung Yun, Tae‐Jin Kim   +12 more
wiley   +1 more source

Methodology for the Analysis of Life Science Innovation Systems (ALSIS) and its Application to Three Case Studies [PDF]

, 2012
Mastroeni, Michele, Mittra, James, Tait, Joyce   +2 more
core  

Medical and economic impacts of managing corneas from older donors at the tissue bank-a single-center retrospective study spanning over 12 years. [PDF]

Front Med (Lausanne)
Hatzfeld AS, Germain N, Maboudou P, Dhayer M, Marchetti P.   +4 more
europepmc   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

A local, non-commercial tissue bank connected to an organ donor program can produce musculoskeletal allografts of uniform quality at very low costs - ten years' experience. [PDF]

Cell Tissue Bank
Azkia H, Harritshøj LH, Nielsen C, Agerlin N, Jensen MG, Hillingsø JG, Andersen PC, Krogsgaard MR.   +7 more
europepmc   +1 more source

A Protein‐Centric Strategy Coupled with Match‐Between‐Run Glycoproteomics Enables Discovery of Robust Site‐Specific Glycan Biomarkers for Hepatocellular Carcinoma

Advanced Science, EarlyView.
In this study, a highly robust N‐glycoproteomics (HRN) platform with a newly developed match‐between‐run scheme is used for biomarker discovery. This study proposes a protein‐centric strategy to prioritize proteins susceptible to aberrant glycosylation.
Lei Liu, Taiheng Ma, Qi Liu, He Zhu, Zheng Fang, Jiahong Ma, Ting Yu, Yan Wang, Jiahua Zhou, Xiaoyan Liu, Yaqian Li, Zhimou Guo, Xinmiao Liang, Mingming Dong, Deguang Sun, Mingliang Ye   +15 more
wiley   +1 more source