Results 61 to 70 of about 191,157 (309)

Bioorthogonal Engineering of Cellular Microenvironments Using Isonitrile Ligations

Advanced Functional Materials, EarlyView.
Highly selective chemistries are required for fabrication and post‐cross–linking modification of cell‐encapsulating hydrogels used in tissue engineering applications. Isonitrile ligation reactions represent a promising class of bioorthogonal chemistries for engineering hydrogel‐based cellular microenvironments. Isonitrile‐based hydrogels are stable and
Ping Zhou, Lauren Brown, Christopher M. Madl   +2 more
wiley   +1 more source

Adalimumab‐Poloxamer Conjugate for Bio‐Better: Enhanced Stability and Function

Advanced Functional Materials, EarlyView.
Antibody‐polymer conjugates, particularly poloxamer conjugates, enhance antibody stability by improving tolerance to physicochemical stress and attenuating proteolysis by proteases. Furthermore, the higher affinity observed with poloxamer conjugation compared to standard PEGylation results in improved therapeutic efficacy in rheumatoid arthritis mouse ...
Jaewon Roh, Sanghee Lee, Soomin Cho, Kun Na   +3 more
wiley   +1 more source

Brain-dead Donation Rate in Month of Ramadan and the other Months: 2005-2014

International Journal of Organ Transplantation Medicine, 2017
Regardless of the level of development, religion and beliefs have crucial impact on people’s attitude towards organ donation. Although organ donation in Islam is obviously appraised, mainly due to lack of an appropriate infrastructure, post-mortem ...
M Aghighi, M Mahdavi-Mazdeh, M Saberi Isfeedvajani, SA Tavakoli, N Tirgar, A Heidary Rouchi   +5 more
doaj  

Understanding the role of mesenchymal stem cells in urinary bladder regeneration—a preclinical study on a porcine model

Stem Cell Research & Therapy, 2018
Background The tissue engineering of urinary bladder advances rapidly reflecting clinical need for a new kind of therapeutic solution for patients requiring urinary bladder replacement.
Marta Pokrywczynska, Arkadiusz Jundzill, Marta Rasmus, Jan Adamowicz, Daria Balcerczyk, Monika Buhl, Karolina Warda, Lukasz Buchholz, Maciej Gagat, Dariusz Grzanka, Tomasz Drewa   +10 more
doaj   +1 more source

Bioinspired Shape Reconfigurable, Printable, and Conductive “E‐Skin” Patch with Robust Antibacterial Properties for Human Health Sensing

Advanced Functional Materials, EarlyView.
In this article, Hojin Kim, Sayan Deb Dutta, and co‐workers report a shape‐reconfigurable, 3D printable, and highly adhesive slime‐like ‘electronic skin’ or ‘E‐skin’ patch for human health sensing and tissue engineering applications. The dual reinforcement of hydrogel patch with carbon nanotubes (CNTs) and cellulose nanocrystals (CNCs) improve the ...
Hojin Kim, Sayan Deb Dutta, Myoung Joon Jeon, Jieun Lee, Hyeonseo Park, Youjin Seol, Ki‐Taek Lim   +6 more
wiley   +1 more source

Bioinspired Design of a Wet‐Adhesive Cornea Glue Based on Recombinant Human Protein Networks

Advanced Functional Materials, EarlyView.
Natures protein‐based high performance materials e.g. elastin, silk and muscle proteins have been mimicked by a new protein‐hybrid material based on redesigned human partial sequences only, showing high wet‐adhesiveness and elasticity for biomedical applications.
Anna Resch, Matthias C. Huber, Alexander Resch, Andreas Schreiber, Thabo Lapp, Jan Dittrich, Frederic Eisen, Austin Julian Michalec, Viktoria Planz, Adrianna Kolberg, Mathaeus Tschaikowsky, Daniel Böhringer, Maike Windbergs, Thomas Reinhard, Bernd Rolauffs, Bizan N. Balzer, Günther Schlunck, Stefan M. Schiller   +17 more
wiley   +1 more source

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo, Muhammad Faisal, Seo‐Hyeon Bae, Kounghwa Youn, Hyo‐Jung Park, Sung Pil Kwon, Il Kwon Hwang, Jisun Lee, Hyeong Jun Kim, Jae‐Hwan Nam, Gyochang Keum, Eun‐Kyoung Bang   +11 more
wiley   +1 more source

Extracellular vesicles from platelet-poor plasma possess anti-inflammatory and anti-catabolic effects in chondrocytes stimulated with IL-1β or synovial membrane-conditioned media

Journal of Orthopaedic Surgery and Research
Background Although osteoarthritis (OA) is the most prevalent form of arthritis, there is still no effective treatment capable of combining immunomodulatory effects with cartilage repair.
Slavomira Gulova, Lucia Slovinska, Livia K. Fecskeova, Jana Bzdilova, Jana Matejova, Marko Moravek, Marek Lacko, Denisa Harvanova   +7 more
doaj   +1 more source

Association of HLA-G 3′ UTR polymorphism and expression with the progression of cervical lesions in human papillomavirus 18 infections

Infectious Agents and Cancer, 2018
Background Human leukocyte antigen (HLA)-G is an immune checkpoint molecule, which expression in cervical cancer cells enables them to escape immunosurveillance.
Hui-Hui Xu, Xia Zhang, Hai-Hong Zheng, Qiu-Yue Han, Ai-Fen Lin, Wei-Hua Yan   +5 more
doaj   +1 more source

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source