Results 71 to 80 of about 458,546 (351)

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Glucocorticoid receptor expression in 20 solid tumor types using immunohistochemistry assay. [PDF]

, 2017
BackgroundGlucocorticoid receptor (GR) activity plays a role in many aspects of human physiology and may play a crucial role in chemotherapy resistance in a wide variety of solid tumors.
Block, Thaddeus S, Lynch, Frank J, Munster, Pamela N, Murphy, Tiffany I, Nguyen, Dat P   +4 more
core   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Efficacy of a single intra-articular injection of mesenchymal stem cells for knee osteoarthritis: a dose-focused meta-analysis of randomized controlled trials

Journal of Orthopaedic Surgery and Research
Background Intra-articular injection of mesenchymal stem cells (MSCs) has emerged as a promising therapy for knee osteoarthritis (OA). However, uncertainty remains regarding the optimal cell dose for maximizing clinical benefit.
Rizki Rahmadian, Zikril Ariliusra, Kevin Rizki Agung Kusuma, Hirowati Ali, Benni Raymond, Riki Meksiko   +5 more
doaj   +1 more source

Design and Validation of a Multiplex KIR and HLA Class I Genotyping Method Using Next Generation Sequencing

Frontiers in Immunology, 2018
Killer cell immunoglobulin-like receptors (KIR), considered the most polymorphic natural killer (NK) cell regulators, bind HLA class-I molecules or still unknown ligands.
Laia Closa, Laia Closa, Francisco Vidal, Francisco Vidal, Francisco Vidal, Maria J. Herrero, Jose L. Caro, Jose L. Caro   +7 more
doaj   +1 more source

Molecular Aspects of Adipose-Derived Stromal Cell Senescence in a Long-Term Culture: A Potential Role of Inflammatory Pathways

Cell Transplantation, 2020
Long-term culture of mesenchymal stromal/stem cells in vitro leads to their senescence. It is very important to define the maximal passage to which the mesenchymal stromal/stem cells maintain their regenerative properties and can be used for cellular ...
Marta Pokrywczynska, Małgorzata Maj, Tomasz Kloskowski, Monika Buhl, Daria Balcerczyk, Arkadiusz Jundziłł, Kamil Szeliski, Marta Rasmus, Tomasz Drewa   +8 more
doaj   +1 more source

Barnes Hospital Bulletin [PDF]

, 1976
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1126/thumbnail ...

core   +1 more source

The TreaT-Assay: A Novel Urine-Derived Donor Kidney Cell-Based Assay for Prediction of Kidney Transplantation Outcome [PDF]

, 2019
Donor-reactive immunity plays a major role in rejection after kidney transplantation, but analysis of donor-reactive T-cells is not applied routinely. However, it has been shown that this could help to identify patients at risk of acute rejection.
Babel, Nina, Choi, Mira, Kurtz, Andreas, Lachmann, Nils, Mueskes, Annemarie, Nickel, Peter, Reinke, Petra, Roch, Toralf, Rosiewicz, Kamil, Schmueck-Henneresse, Michael, Stein, Maik, Stervbo, Ulrik, Thieme, Constantin J., Wehler, Patrizia, Weist, Benjamin J. D., Westhoff, Timm H.   +15 more
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Fibrin gel as a scaffold for skin substitute – production and clinical experience

Acta Clinica Croatica, 2016
The purpose of this study was to create a fibrin-based human skin substitute in vitro with epidermal and dermal component and to assess its healing potential in deep partial and full thickness burns.
Antun Kljenak, Mirna Tominac Trcin, Marina Bujić, Tamara Dolenec, Martina Jevak, Gordan Mršić, Gordana Zmiš, Zoran Barčot, Ante Muljačić, Maja Popović   +9 more
doaj   +1 more source