Results 51 to 60 of about 34,845 (312)

Musculoskeletal Tissue Banking in Singapore: 15 Years of Experience (1988–2003)

Journal of Orthopaedic Surgery, 2004
Purpose. To report 15 years' experience of musculoskeletal tissue banking by the National University Hospital Tissue Bank. Methods. This study describes the development of Singapore's national bone bank since its establishment in 1988.
A Nather
doaj   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Posterior Lamellar Graft Preparation: A Prospective Review from an Eye Bank on Current and Future Aspects

Journal of Ophthalmology, 2013
Descemet membrane endothelial keratoplasty (DMEK) is a corneal surgical technique which selectively replaces the damaged posterior part of the cornea with a healthy donor graft retaining the rest of the tissue intact.
Mohit Parekh, Gianni Salvalaio, Alessandro Ruzza, Davide Camposampiero, Carlo Griffoni, Alfonso Zampini, Diego Ponzin, Stefano Ferrari   +7 more
doaj   +1 more source

Transgender Corneal Donors: A Dilemma Worthy of Attention

Ophthalmology and Therapy, 2018
Currently, there are no specific guidelines in place to direct eye banks on how to deal with donated tissue from transgender individuals. This commentary will examine the history of corneal transplantation and the importance of the corneal tissue donor ...
Majid Moshirfar, Tanner W. Brown, Jackson L. Goldberg, William D. Wagner, Yasmyne C. Ronquillo   +4 more
doaj   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Postoperative detection of unusual pathology in donor corneal tissue

Indian Journal of Ophthalmology, 2019
We present a series of three patients with previously undetected corneal pathology in grafted corneal tissue following keratoplasty for keratoconus. Postoperatively, a faint layer of anterior stromal haze involving the graft was observed in each patient ...
Louis J Stevenson, Graeme Pollock, Rasik B Vajpayee   +2 more
doaj   +1 more source

A Novel C19orf47‐AKT2 Chimeric RNA Generated by Cis‐Splicing of Adjacent Genes Is Associated With Glioblastoma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Malignant gliomas pose significant therapeutic challenges. This study aimed to identify and characterize a novel chimeric RNA in glioma and assess its clinical and functional significance for precision treatment. Methods The C19orf47‐AKT2 chimeric RNAs were identified through RNA sequencing and validated by polymerase chain reaction.
Zihan Wang, Bowen Ni, Kezhi Wu, Qi Zhang, Jinglin Guo, Runwei Yang, Ziyu Wang, Guozhong Yi, Guanglong Huang, Minyi He, Yimin Xu, Yawei Liu   +11 more
wiley   +1 more source

cGMP-Manufactured Human Induced Pluripotent Stem Cells Are Available for Pre-clinical and Clinical Applications

Stem Cell Reports, 2015
The discovery of induced pluripotent stem cells (iPSCs) and the concurrent development of protocols for their cell-type-specific differentiation have revolutionized our approach to cell therapy.
Behnam Ahmadian Baghbaderani, Xinghui Tian, Boon Hwa Neo, Amy Burkall, Tracy Dimezzo, Guadalupe Sierra, Xianmin Zeng, Kim Warren, Don Paul Kovarcik, Thomas Fellner, Mahendra S. Rao   +10 more
doaj   +1 more source

Influence of submerged macrophytes on phosphorus in a eutrophic reservoir in a semiarid region

Journal of Limnology, 2020
Phosphorus (P) is the main nutrient responsible for the harmful effects caused by the enrichment of aquatic systems, and submerged macrophytes play an important role in this process, since they can both remove and release this nutrient in environmental ...
Vanessa Virginia Barbosa, Juliana dos Santos Severiano, Dayany Aguiar de Oliveira, José Etham de Lucena Barbosa   +3 more
doaj   +1 more source

NOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by NOTCH2NLC GGC repeat expansions, with heterogeneous clinical manifestations, including parkinsonism. Recent studies have identified NOTCH2NLC repeat expansions in patients with Parkinson's disease (PD) and atypical parkinsonism (aPM), suggesting ...
Han‐Lin Chiang, Kang‐Yang Jih, Cheng‐Tsung Hsiao, Fu‐Pang Chang, Justus Chunyu Chen, Yi‐Chu Liao, Yih‐Ru Wu, Yi‐Chung Lee   +7 more
wiley   +1 more source