Results 101 to 110 of about 1,553,407 (312)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Image standards in Tissue-Based Diagnosis (Diagnostic Surgical Pathology)

open access: yesDiagnostic Pathology, 2008
Background Progress in automated image analysis, virtual microscopy, hospital information systems, and interdisciplinary data exchange require image standards to be applied in tissue-based diagnosis. Aims To describe the theoretical background, practical
Vollmer Ekkehard   +5 more
doaj   +1 more source

Towards objective endoscopic diagnosis of Barrett's associated early neoplasia using fibre-optic Raman Spectroscopy [PDF]

open access: yes, 2012
This translational research evaluates a novel, custom-built Raman probe for potential application as an in vivo diagnostic tool in the oesophagus.
Almond, Laurence Maximilian
core  

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Diagnosis of rectal cancer by Tissue Resonance Interaction Method

open access: yesBMC Gastroenterology, 2010
Background Since population screening has the potential to reduce mortality from rectal cancer (RC), novel methods with improved cost-effectiveness warrant consideration.
Poiasina Elia   +3 more
doaj   +1 more source

Use of Tissue and Tumour Markers in the Histological Diagnosis of Tumours

open access: yes, 1984
Tissue and tumour markers may be of help in establishing the diagnosis of tumours. In this study I have evaluated the use of several tissue and tumour markers in the histological diagnosis of certain tumours.
Om, Anil
core  

Tumor markers in breast cancer - European Group on Tumor Markers recommendations [PDF]

open access: yes, 2005
Recommendations are presented for the routine clinical use of serum and tissue-based markers in the diagnosis and management of patients with breast cancer.
Einarsson, Roland   +10 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

A practical risk stratification system based on ultrasonography and clinical characteristics for predicting the malignancy of soft tissue masses

open access: yesInsights into Imaging
Objective To establish a practical risk stratification system (RSS) based on ultrasonography (US) and clinical characteristics for predicting soft tissue masses (STMs) malignancy.
Ying-Lun Zhang   +13 more
doaj   +1 more source

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