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Distribution of ceftazidime in rat tissues

Biopharmaceutics & Drug Disposition, 1998
The pharmacokinetics and tissue distribution of ceftazidime (CFT), a third generation cephalosporin antibiotic commonly used in clinical practice, were investigated in rats after intravenous administration of the antibiotic. Studies using intravenous bolus administration were carried out at two dose levels (5 and 20 mg) of the antibiotic.
L, Granero   +3 more
openaire   +2 more sources

Tissue Phospholipid Distribution in Adrenalectomized Rats

Endocrinology, 1967
Bilateral adrenalectomy altered phospholipid distribution in various tissues of the rat. Total phospholipids were drastically reduced in liver, heart and kidney; the change in brain was much less significant. Phospholipid fractionation was performed by paper chromatography on extracts of these tissues.
D R, Chowdhury, D K, Belsare
openaire   +2 more sources

Distribution of methotrexate in rat tissues

British Journal of Dermatology, 1974
SUMMARY The distribution of methotrexate between tissues is a very complex process, dependent in part upon the species studied, the size of the dose and the channel of administration. The nature of the tissue and its content of dihydrofolate reductase also play a part. Elimination of methotrexate in the urine and bile indicate that renal and hepatic
openaire   +2 more sources

Tissue Distribution of Tetrahydrobiopterin Generating Enzymes

1993
Tetrahydrobiopterin (BH4) is the natural cofactor of Phenylalanine, tyrosine and tryptophan hydroxylases as well as nitric oxide synthase1-5. BH4 is synthesized from GTP by successive actions of at least three enzymes2,6, namely, GTP cyclohydrolase I, 6-pyruvoyltetrahydropterin synthase (PTPS) and sepiapterin reductase (SR)2,6.
M, Hoshiga, K, Hatakeyama, H, Kagamiyama
openaire   +2 more sources

Fluoride tissue distribution: short-term kinetics

American Journal of Physiology-Renal Physiology, 1979
The short-term distribution kinetics of 18F, with and without added carrier, were studied in 12 soft tissues and femur following intravenous administration in rats. The animals were killed in groups of four at 5, 10, 15, 20, 30, and 60 min after the dose.
G M, Whitford   +2 more
openaire   +2 more sources

Pressure Distribution in Tissue

2019
This chapter introduces estimates and measurements of the pressure distribution in tissue. Several physical and computer models are included to show the results of estimating tissue pressure distribution. Experimental results suggest causes of pressure sore formation.
openaire   +1 more source

Tissue distribution of human chorionic gonadotropin

American Journal of Obstetrics and Gynecology, 1970
Abstract Tissue distribution of exogenous HCG was studied in adult female mice injecting the animals with HCG-I 125 , BSA-I 125 , and I 125 and determining in a scintillation counter the tissue radioactivity at various time intervals. The radioactive materials were extracted from the tissues and mixed with excess anti-HCG serum. It was found that the
S, Kazeto, M M, Hreshchyshyn
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TISSUE DISTRIBUTION OF CHANNEL CATFISH VIRUS

Journal of Wildlife Diseases, 1971
The kidney, liver, intestine, brain, and muscle of live infected channel catfish were assayed for channel catfish virus in channel catfish gonad cell cultures. Sampling was done at 24-hour intervals for 120 hours. The virus was first detected in the kidneys of channel catfish 24 hours after inoculation.
openaire   +2 more sources

Endocannabinoid System Components: Overview and Tissue Distribution.

Advances in Experimental Medicine and Biology, 2019
Neal Joshi, E. Onaivi
semanticscholar   +1 more source

Accumulation, tissue distribution, and biochemical effects of polystyrene microplastics in the freshwater fish red tilapia (Oreochromis niloticus).

Environmental Pollution, 2018
Jian-nan Ding   +4 more
semanticscholar   +1 more source

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