Validating potential organ and tissue donors in the middle of the COVID-19 pandemic: Scoping review and recommendations construction. [PDF]
da Silva-Knihs N+6 more
europepmc +1 more source
Transient receptor potential melastatin‐4 (TRPM4) is overexpressed in prostate cancer (PCa). Knockout of TRPM4 resulted in reduced PCa tumor spheroid size and decreased PCa tumor spheroid outgrowth. In addition, lack of TRPM4 increased cell death in PCa tumor spheroids.
Florian Bochen+6 more
wiley +1 more source
Retrospective study of COVID-19 seroprevalence among tissue donors at the onset of the outbreak before implementation of strict lockdown measures in France. [PDF]
Germain N+6 more
europepmc +1 more source
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti+8 more
wiley +1 more source
Blood-borne viral infections among blood, organ and tissue donors
The article presents an actual information on the detection rate of blood-borne viral infections (BBVI) among blood donors, potential organ and tissue donors in Russia and other countries. The causes of differences in BBVI prevalence between blood donors
M. Sh. Khubutiya+3 more
doaj
A new pharmacological preconditioning-based target: from drosophila to kidney transplantation [PDF]
One of the biggest challenges in medicine is to dampen the pathophysiological stress induced by an episode of ischemia. Such stress, due to various pathological or clinical situations, follows a restriction in blood and oxygen supply to tissue, causing a shortage of oxygen and nutrients that are required for cellular metabolism.
arxiv
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis
One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen+3 more
wiley +1 more source
Profile of potential organ donors in a reference hospital [PDF]
The study aimed to characterize the profile of potential organ donors in a hospital in the northern zone of Ceará, Brazil. This is a quantitative, retrospective and documentary study, performed in a hospital of Ceará, from information contained in the ...
Thamy Braga Rodrigues+5 more
doaj
Femoral fracture load and damage localisation pattern prediction based on a quasi-brittle law : linear and non-linear FE meshing [PDF]
Finite element analysis is one of the most used tool for studying femoral neck fracture. Nerveless, consensus concerning either the choice of material characteristics, damage law and /or geometric models (linear on nonlinear) still remains unreached.
arxiv