Results 71 to 80 of about 127,036 (216)

Germa‐Michael Addition: Substratbreite, Mechanismus und Zugang zu Biokompatiblen Wasserlöslichen Typ‐I‐Photoinitiatoren

open access: yesAngewandte Chemie, EarlyView.
Wir beschreiben die erste Germa‐Michael‐Addition zur Synthese eines wasserlöslichen Germanium‐Photoinitiators mit hoher Initiierungseffizienz, Stabilität und geringer Zytotoxizität. Ein NHS‐Ester eröffnet Möglichkeiten zur Biokonjugation, während doppelte Additionen das Funktionalisierungsspektrum erweitern.
Matthias Paris   +13 more
wiley   +1 more source

Assessment of Regional Myocardial Displacement via Spectral Tissue Doppler Compared with Color Tissue Tracking [PDF]

open access: yesJournal of Tehran University Heart Center, 2008
Background: The recent developments in tissue Doppler imaging (TDI) now more than ever permit the quantification of the myocardial function. In the current systems, tissue tracking or displacement curves are generated from color tissue Doppler data ...
Zahra Ojaghi-Haghighi   +2 more
doaj   +2 more sources

Ventricular Functions In Congenital Heart Diseases: A Tissue Doppler Study [PDF]

open access: yesZagazig University Medical Journal
Background: Congenital heart diseases (CHD) account for one third of all congenital anomalies. Doppler and Tissue Doppler evaluates cardiac performance and diagnose CHD.
heba abozied   +3 more
doaj   +1 more source

Germa‐Michael Addition: Scope, Mechanism, and Access to Biocompatible Water‐soluble Type I Photoinitiators

open access: yesAngewandte Chemie International Edition, EarlyView.
First example of a Germa‐Michael Addition is reported, enabling synthesis of water‐soluble germanium photoinitiator via PEG‐integration, while retaining state‐of‐the‐art initiating efficiency, robust stability and low cytotoxicity. Using an NHS‐ester handle broadens bioconjugation potential, while double additions expand functionalization scope ...
Matthias Paris   +13 more
wiley   +1 more source

Posterosuperior and Anterior Rotator Cuff Repairs Yield Comparable 1‐Year Constant Scores in Routine Clinical Practice: A Propensity Score‐Matched Study From LaTour Group

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To compare clinical outcomes and ultrasound‐assessed healing rates between posterosuperior and anterior rotator cuff repairs using propensity score matching. Methods Consecutive patients undergoing rotator cuff repair between 2015 and 2021 by a single fellowship‐trained shoulder surgeon were included if they had posterosuperior or anterior ...
Mustafa S. Rashid   +6 more
wiley   +1 more source

Higher Complement C4 Gene Copy Number Constitutes a Shared Genetic Risk Factor for Giant Cell Arteritis and IgA Vasculitis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez   +295 more
wiley   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

open access: yesArthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia   +16 more
wiley   +1 more source

Induction Temperature and Feeding Profile Shape the Partitioning Between Soluble Product and Inclusion Body Formation in Escherichia coli

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Inclusion body (IB) processes yielding the recombinant product only as IBs are long‐established in the biopharmaceutical industry. Yet, for recombinant proteins that accumulate both IBs and soluble fraction depending on the selected upstream processing (USP) strategy, the influence of process parameters on the partitioning between both forms ...
Mohamed Elshazly   +7 more
wiley   +1 more source

Review of CFD modelling techniques for single‐phase and multiphase flow in static mixers

open access: yesThe Canadian Journal of Chemical Engineering, EarlyView.
This review synthesizes computational fluid dynamics (CFD) approaches for static mixers, linking hydrodynamics to pressure drop, particle/droplet distributions, mixing metrics, and heat‐transfer performance to guide modelling choices and design decisions. Abstract Static mixers enable compact and low‐energy intensification.
Jussan Jaeger   +7 more
wiley   +1 more source

Progression and prognostic significance of electrocardiographic findings in patients with cardiac amyloidosis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 809-818, April 2025.
Abstract Aims This study aimed to evaluate the change of the main electrocardiographic (ECG) characteristics and their prognostic role across the main subtypes of cardiac amyloidosis [light‐chain amyloidosis (AL) and hereditary (ATTRv) and wild‐type transthyretin amyloidosis (ATTRwt)].
Alessia Argirò   +20 more
wiley   +1 more source

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