Results 101 to 110 of about 36,495 (251)

Role of reactive oxygen species in mediating peripheral hypoxic vasodilation and sympathoexcitation at high altitude

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude acclimatisation increases muscle sympathetic nerve activity (MSNA) via activation of the arterial chemoreflex, pulmonary arterial baroreceptors and resetting of the sympathetic vascular baroreflex. However attempting to silence these mechanisms only partially normalises MSNA, implicating other contributory ...
Liam D. Corr   +15 more
wiley   +1 more source

ROC‐325 Attenuates Hypoxia‐Induced Pulmonary Hypertension Through Dual Inhibition of Autophagy and Hypoxia‐Inducible Factor 2α Signaling

open access: yesMedComm – Future Medicine, Volume 5, Issue 1, March 2026.
In hypoxia‐induced pulmonary hypertension, endothelial HIF‐2α accumulation and autophagic activation drive vascular remodeling. We demonstrate that the novel lysosomal inhibitor ROC‐325 simultaneously attenuates this pathogenic autophagy and promotes HIF‐2α degradation.
Changlei Bao   +18 more
wiley   +1 more source

Disseminated Invasive Aspergillosis in a Young Patient With Chronic Alcohol Use and Seemingly Preserved Immunocompetence: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Invasive aspergillosis, though typically seen in immunocompromised patients, can also affect immunocompetent individuals and mimic pulmonary malignancy. This case highlights the importance of considering fungal infections in the differential diagnosis of chronic respiratory symptoms, particularly in patients with risk factors such as heavy ...
Kumail Khandwala   +4 more
wiley   +1 more source

The Impact of High‐Intensity Exercise in Normobaric Hypoxia on Right Ventricular Function in Trained and Untrained Men—An Echocardiographic Study

open access: yesComprehensive Physiology, Volume 16, Issue 1, February 2026.
A single bout of high‐intensity exercise to volitional exhaustion under acute normobaric hypoxia (~3000 m a.s.l.; FiO2 = 14.4%) does not induce greater alterations in right ventricular systolic function compared to normoxia in either trained or untrained healthy men.
Gajda Robert   +8 more
wiley   +1 more source

Evaluation of Early Alterations in Transmitral Diastolic Flow and Tissue Doppler Findings of the Septal and Lattral Segments of Left Ventricles in Early Period after Coronary Angioplasty

open access: yesمجله دانشکده پزشکی اصفهان, 2011
Background: We aimed to evaluate subepicardial and subendocardial left ventricular (LV) functions in patients with single coronary artery lesion at early stage after percutaneous coronary intervention (PCI).
Hasan Shemirani   +2 more
doaj  

Predicting left ventricular filling pressure by tissue Doppler echocardiography in inten-sive care. [PDF]

open access: bronze, 2006
Martin Hutyra   +5 more
openalex   +1 more source

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