Results 41 to 50 of about 242,093 (272)
Group 2 Innate Lymphoid Cells Are Redundant in Experimental Renal Ischemia-Reperfusion Injury. [PDF]
, 2019 Acute kidney injury (AKI) can be fatal and is a well-defined risk factor for the development of chronic kidney disease. Group 2 innate lymphoid cells (ILC2s) are innate producers of type-2 cytokines and are critical regulators of homeostasis in ...
Cameron, Guy JM +9 more
core +4 more sources
Comparison of Varying Tissue Freezing Methods on Murine Colonic Tissue [PDF]
, 2018 Histology often requires a tissue specimen to be embedded so that it may be sectioned, stained, and mounted on a microscope slide for viewing. One common method of tissue embedding for rapid histology is freezing, since freezing allows tissue to be ...
Hughes, James
core +2 more sources
Partition Decoupling for Multi-gene Analysis of Gene Expression Profiling Data [PDF]
, 2011 We present the extention and application of a new unsupervised statistical learning technique--the Partition Decoupling Method--to gene expression data.
Braun, Rosemary +3 more
core +5 more sources
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
COSMOS: a platform for real-time morphology-based, label-free cell sorting using deep learning
Communications Biology, 2023 Cells are the singular building blocks of life, and a comprehensive understanding of morphology, among other properties, is crucial to the assessment of underlying heterogeneity.
Mahyar Salek +22 more
doaj +1 more source
Monoclonal antibodies against human astrocytomas and their reactivity pattern [PDF]
, 1987 The establishment of hybridomas after fusion of X63-Ag8.653 mouse myeloma cells and splenocytes from mice hyperimmunized against human astrocytomas is presented. The animals were primed with 5 × 106 chemically modified uncultured or cultured glioma cells.
B. Martin +36 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Frontiers in Molecular Biosciences, 2022 Human disease states are biomolecularly multifaceted and can span across phenotypic states, therefore it is important to understand diseases on all levels, across cell types, and within and across microanatomical tissue compartments.
Jessica K. Lukowski +19 more
doaj +1 more source
Experimental Control and Characterization of Autophagy in Drosophila [PDF]
, 2008 Insects such as the fruit fly Drosophila melanogaster, which fundamentally reorganize their body plan during metamorphosis, make extensive use of autophagy for their normal development and physiology.
A.D. Velentzas +18 more
core +1 more source
OCT-Embedded Tissue Preparation v1
, 2022 This protocol describes embedding of tissue samples in optimal cutting temperature (OCT) compound (Lin & Lin, 2020). Tissue embedded in OCT can then undergo frozen sectioning on a microtome-cryostat. The advantage of OCT embedding is it requires minimal tissue processing and tissue does not need to undergo fixation prior to snap freezing.
Stephen Fisher +10 more
openaire +1 more source