Results 331 to 340 of about 6,889,134 (415)

Expanding the Applicability of Electroactive Polymers for Tissue Engineering Through Surface Biofunctionalization. [PDF]

open access: yesBiomimetics (Basel)
Leiva B   +5 more
europepmc   +1 more source

FSH enhances the inflammatory response of macrophages in the knee joint possibly through the NFκB pathway

open access: yesFEBS Open Bio, Volume 15, Issue 4, Page 622-633, April 2025.
We explored the role of FSH on the synovium and found that FSH was able to mediate the development of osteoarthritis by acting on the FSH receptor (FSHR) to promote the production and release of inflammatory factors through the activation of the NFκB signaling pathway. Previous studies have suggested that women with higher follicle‐stimulating hormone (
Yu Chen   +6 more
wiley   +1 more source

Dexmedetomidine suppresses glucose‐stimulated insulin secretion in pancreatic β‐cells

open access: yesFEBS Open Bio, Volume 15, Issue 4, Page 634-646, April 2025.
Dexmedetomidine decreases insulin release and affects glucose metabolism; however, the specific mechanism remains largely unknown. This study shows clinically relevant doses of dexmedetomidine suppressed glucose‐stimulated insulin secretion. There was no significant difference in oxygen consumption rate, intracellular ATP levels, or caspase‐3/7 ...
Munenori Kusunoki   +5 more
wiley   +1 more source

CDK5 interacts with MST2 and modulates the Hippo signalling pathway

open access: yesFEBS Open Bio, Volume 15, Issue 4, Page 647-660, April 2025.
By using a yeast‐two‐hybrid system, immune precipitation and a proteomics approach, we identify a novel interaction between CDK5 and MST2, which modulates the mechano‐sensitive Hippo signalling pathway in a liver tumour cell line. MST2 (STK3) is a major upstream kinase in the Hippo signalling pathway, an evolutionary conserved pathway in regulation of ...
Mehak Passi   +5 more
wiley   +1 more source

Small spheroids for head and neck cartilage tissue engineering. [PDF]

open access: yesSci Rep
Reutter S   +4 more
europepmc   +1 more source

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

open access: yesFEBS Open Bio, Volume 15, Issue 5, Page 726-737, May 2025.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang   +11 more
wiley   +1 more source

Surface modification of electrospun polycaprolactone and zein using cold atmospheric plasma for tissue engineering applications. [PDF]

open access: yesSci Rep
Esmaeili Ranjbar A   +8 more
europepmc   +1 more source

Development of biomaterials for bone tissue engineering based on bile acids. [PDF]

open access: yesJ Mater Sci Mater Med
Liu Y   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy