Results 31 to 40 of about 58,158 (248)

Rapid Maxillary Expansion on the Adolescent Patient: Systematic Review and Case Report

Children, 2022
Aim: In the literature, many studies and articles are investigating new devices and approaches to achieve rapid palate expansion through the opening of the palatal suture, and evaluating the skeletal, dental, and soft tissue effects.
Alessio Danilo Inchingolo, Irene Ferrara, Fabio Viapiano, Anna Netti, Merigrazia Campanelli, Silvio Buongiorno, Giulia Latini, Vincenzo Carpentiere, Anna Maria Ciocia, Sabino Ceci, Assunta Patano, Fabio Piras, Filippo Cardarelli, Damiano Nemore, Giuseppina Malcangi, Angela Di Noia, Antonio Mancini, Angelo Michele Inchingolo, Grazia Marinelli, Biagio Rapone, Ioana Roxana Bordea, Antonio Scarano, Felice Lorusso, Daniela Di Venere, Francesco Inchingolo, Gianna Dipalma   +25 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Early experiences with robot-assisted prosthetic breast reconstruction

Archives of Plastic Surgery, 2019
Robotic surgery facilitates surgical procedures by employing flexible arms with multiple degrees of freedom and providing high-quality 3-dimensional imaging.
Sung Jae Ahn, Seung Yong Song, Hyung Seok Park, Se Ho Park, Dae Hyun Lew, Tai Suk Roh, Dong Won Lee   +6 more
doaj   +1 more source

GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC. [PDF]

PLoS ONE, 2012
BACKGROUND: Mesenchymal stromal cells (MSC) have gained importance in tissue repair, tissue engineering and in immunosupressive therapy during the last years.
Natalie Fekete, Markus T Rojewski, Daniel Fürst, Ludwika Kreja, Anita Ignatius, Julia Dausend, Hubert Schrezenmeier   +6 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The Effects of Negative Pressure by External Tissue Expansion Device on Epithelial Cell Proliferation, Neo-Vascularization and Hair Growth in a Porcine Model

PLOS ONE, 2016
While pre-treating a fat transplant recipient site with negative pressure has shown promise for increasing the fat survival rate, the underlying mechanisms have not been investigated, partly due to challenges related to immobilization of vacuum domes on large animal subjects.
Hui-Yi Hsiao, Jia-Wei Liu, Eric M Brey, Ming-Huei Cheng   +3 more
openaire   +4 more sources

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Engineering Smart Hybrid Tissues with Built-In Electronics

iScience, 2020
One of the major hurdles faced in tissue engineering is the inability to monitor and control the function of an engineered tissue following transplantation.
Ron Feiner, Tal Dvir
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source