Results 301 to 310 of about 1,251,677 (333)

Infrared Neural Stimulation Elicits Distinct Molecular Pathways in Astrocytes Based on Laser Pulse Parameters

Advanced Biology, EarlyView.
Infrared (IR) light evokes distinct calcium and water transport responses in astrocytes, depending on stimulation duration and protocol. This study uses widefield imaging and pharmacology to reveal differential engagement of astroglial signaling pathways.
Wilson R. Adams, Ana I Borrachero‐Conejo, Pratheepa Kumari Rasiah, Emanuela Saracino, Roberto Zamboni, Eric Duco Jansen, Valentina Benfenati, Anita Mahadevan‐Jansen   +7 more
wiley   +1 more source

Amide‐Linked Local Anesthetics Alter Tumor Biology in a Complex Human Tissue Model of Non‐Small Cell Lung Adenocarcinoma

Advanced Biology, EarlyView.
Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer, Sebastian Krämer, Ngoc Anh Hoang, Doreen Sittig, Isabella Metelmann, Uta‐Carolin Pietsch, Sebastian N. Stehr, Sonja Kallendrusch, Tobias Piegeler   +8 more
wiley   +1 more source

EPA and DHA inhibit LDL-induced upregulation of human adipose tissue NLRP3 inflammasome/IL-1β pathway and its association with diabetes risk factors

Valérie Lamantia, Simon Bissonnette, Myriam Beaudry, Yannick Cyr, Christine Des Rosiers, Alexis Baass, May Faraj   +6 more
openalex   +1 more source

Loss of Stat3 in Prx1+ Progenitors Impairs Molar Root Development

Advanced Biology, EarlyView.
Stat3 critically regulates mandibular first molar and alveolar bone morphogenesis. Conditional ablation of Stat3 disrupts the osteogenic capacity of Prx1+ mesenchymal progenitors, as evidenced across in vivo and in vitro models. Abstract Signal Transducer and Activator of Transcription 3 (Stat3) acts as a central transcriptional modulator coordinating ...
Xin Feng, Wangyu Luo, Yichen Yao, Lichieh Lin, Laiting Chan, Jiarui Lu, Zijing Huang, Jingyi Feng, Le Zhao, Xiaolei Zhang, Liu Yang   +10 more
wiley   +1 more source

Poor correlation using two functional amidolytic methods for tissue factor pathway inhibitor

, 2000
MJ Adams, R Oostryck
openalex  

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Marstacimab, a tissue factor pathway inhibitor neutralizing antibody, improves coagulation parameters of ex vivo dosed haemophilic blood and plasmas

Haemophilia, 2019
Tissue factor pathway inhibitor (TFPI) is an endogenous inhibitor of the extrinsic pathway that negatively regulates thrombin production during coagulation.
S. Patel-Hett, E. Martin, B. Mohammed, S. Rakhe, P. Sun, J. C. Barrett, M. Nolte, J. Kuhn, D. Pittman, John E. Murphy, D. Brophy   +10 more
semanticscholar   +1 more source

The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies

Ca-A Cancer Journal for Clinicians, 2022
Sharon Elad, Noam Yarom, Yehuda Zadik
exaly  

Tissue Factor and Tissue Factor Pathway Inhibitor in Nasal Mucosa and Nasal Secretions of Chronic Rhinosinusitis with Nasal Polyp

American Journal of Rhinology & Allergy, 2015
S. Shimizu, T. Ogawa, Kumiko Takezawa, I. Tojima, H. Kouzaki, Takeshi Shimizu   +5 more
semanticscholar   +1 more source

Tissue Factor Pathway Inhibitor: Then and Now

Seminars in Thrombosis and Hemostasis, 2014
P. Ellery, M. Adams
semanticscholar   +1 more source

Structure and Biology of Tissue Factor Pathway Inhibitor

Thrombosis and Haemostasis, 2001
J. Birktoft, S. Steer, S. P. Bajaj, M. Bajaj   +3 more
semanticscholar   +1 more source