Results 141 to 150 of about 174,270,932 (291)

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

Significance Level of Pleural Fluid Tissue Inhibitor Metalloproteinase-1 (TIMP-1) and Glucose Levels as Biomarkers of Malignant Pleural Effusion

Jurnal Respirasi
Introduction: Distinguishing between malignant and non-malignant pleural effusions is often challenging due to overlapping biochemical profiles. Conventional diagnostic methods, including cytology and biopsy, are limited by their invasive nature, high ...
Cleine Michaela, Ngakan Putu Parsama Putra, Susanthy Djajalaksana, Nanik Setijowati, Aditya Sri Listyoko   +4 more
doaj   +1 more source

Higher serum tissue inhibitor of metalloproteinase-1 predicts atrial fibrillation recurrence after radiofrequency catheter ablation. [PDF]

Front Cardiovasc Med, 2022
Li H, Sun W, Wang Z, Wang Z, Du X, Chen J, Gao J, Liu X, Wang X, Wang Y, Wu Y, Zhang X.   +11 more
europepmc   +1 more source

Levels of matrix metalloproteinase (MMP) -7,-8,-9 and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in acute pancreatitis (AP) patients and controls.

, 2016
Levels of matrix metalloproteinase (MMP) -7,-8,-9 and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in acute pancreatitis (AP) patients and controls.
Johanna Hästbacka (735749), Eeva Moilanen (23357), Eija Nukarinen (3080463), Leena Kylänpää (3080460), Outi Lindström (3080457), Mari Hämäläinen (689956), Pauli Puolakkainen (64908), Antti Kuuliala (793574), Ville Pettilä (2504218), Krista Kuuliala (793573), Heikki Repo (64913)   +10 more
core   +1 more source

Engineered Cyanobacteria‐Hydrogel Microecological System for Oxygen Reprogramming Synergizes Immunomodulation With Anabolism in Osteoarthritis Therapy

Advanced Science, EarlyView.
An injectable cyanobacteria‐laden hydrogel enables light‐dependent oxygen metabolism engineering for osteoarthritis therapy. Photosynthetic oxygen release under red light irradiation suppresses synovial inflammation via HIF‐1α inhibition and M2 macrophage polarization, while respiratory oxygen consumption in darkness stabilizes chondrocyte HIF‐1α to ...
Lerong Yang, Chong Shen, Hongjun Huang, Siyi Liu, Zeyu Huang, Licheng Xi, Huan Cao, Li Zheng, Zainen Qin   +8 more
wiley   +1 more source

Elevated tissue inhibitor of metalloproteinase-1 along with left atrium hypertrophy predict atrial fibrillation recurrence after catheter ablation. [PDF]

Front Cardiovasc Med, 2022
Sun W, Li H, Wang Z, Li Q, Wen H, Wu Y, Du J.   +6 more
europepmc   +1 more source

Tissue inhibitor of metalloproteinase-1 [PDF]

, 2018
S. Holdenrieder, P. Stieber
openaire   +1 more source

SynNotch Receptors for Visualizing Immunoreceptor Force Transmission and Downstream Signaling In Vivo

Advanced Science, EarlyView.
A mechanically activated SynNotch reporter platform enables detection of force transmission through receptors as they mediate immune cell interactions. Targeting CD40 on B cells and TCR on T cells records force‐induced reporter activation across 2D coculture, 3D organoid, and implanted in mice, which also reveal force‐amplification of immune receptor ...
Menglan Li, Jintian Lyu, Kaitao Li, Ameya Dravid, Deepali Balasubramani, Amir H. K. Ashkezari, Hyun‐Kyu Choi, Gabriel A. Kwong, Ankur Singh, Cheng Zhu   +9 more
wiley   +1 more source

Are Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 Useful as Markers in Diagnostic Management of Children with Newly Diagnosed Ulcerative Colitis? [PDF]

J Clin Med, 2022
Czajkowska A, Guzinska-Ustymowicz K, Pryczynicz A, Lebensztejn D, Daniluk U.   +4 more
europepmc   +1 more source

Effect of recombinant human tissue inhibitor of matrix metalloproteinase-1 in rabbit mandibular distraction osteogenesis: a histological and immunohistochemical study

, 2006
Background: Bone matrix metalloproteinases are capable of degrading bone matrix during the remodelling, and their degradation activities can be down regulated by the tissue inhibitors of matrix metalloproteinases.
Zheng, L, Li Wu Zheng, A. Bakr M. Rabie, Rabie, ABM, Lim Kwong Cheung, Li Ma, Cheung, LK, Ma, L   +7 more
core   +1 more source