Results 221 to 230 of about 92,606 (252)

Effect of psoriasis treatment on plasma concentrations of metalloproteinase‐1 and tissue inhibitor of metalloproteinases‐1

Journal of the European Academy of Dermatology and Venereology, 2005
ABSTRACTAim  The aim of this study was to evaluate the effect of psoriasis treatment on plasma concentrations of metalloproteinase‐1 (MMP‐1) and tissue inhibitor of metalloproteinases‐1 (TIMP‐1) with respect to disease severity.Methods  MMP‐1 and TIMP‐1 were measured using an enzyme immunoassay in plasma of 32 patients before and after topical ...
I, Flisiak, H, Myśliwiec, B, Chodynicka
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Levels of tissue inhibitor of metalloproteinases-1 in blood transfusion components

Scandinavian Journal of Clinical and Laboratory Investigation, 2002
Blood transfusion during surgery for solid tumors may reduce patient survival because of various bioactive substances present in blood preparations. The anti-proteolytic protein tissue inhibitor of metalloproteinases-1 (TIMP-1) present in large quantities in platelets has been shown to stimulate cell growth and to inhibit apoptosis and may therefore be
M N, Holten-Andersen, N, Brunner, I J, Christensen, V, Jensen, H J, Nielsen   +4 more
openaire   +2 more sources

Sp1‐dependent regulation of the tissue inhibitor of metalloproteinases‐1 promoter

Journal of Cellular Biochemistry, 2004
AbstractExtracellular matrix (ECM) remodeling is involved in many cellular properties such as division, migration, differentiation, and death. The turnover of ECM is regulated by matrix metalloproteinases (MMPs) and the MMPs are inhibited by the tissue inhibitors of metalloproteinases (TIMPs). In this study, the transcriptional regulation of the TIMP‐1
Minhyung, Lee, Sun U, Song, Ji Kan, Ryu, Jun Kyu, Suh   +3 more
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Molecular characteristics of equine stromelysin and the tissue inhibitor of metalloproteinase 1

American Journal of Veterinary Research, 1998
Abstract Objective To clone the entire coding sequence of equine matrix metalloproteinase-3 (MMP-3, stromelysin) and tissue inhibitor of metalloproteinase-1 (TIMP-1 ) and compare their nucleotide and amino acid sequences with those of MMP-3 and TIMP-1 from other species.
D W, Richardson, G R, Dodge
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Purification and secondary structural analysis of tissue inhibitor of metalloproteinases- 1

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1994
In connective tissue diseases such as rheumatoid arthritis, the matrix metalloproteinases are the primary enzymes involved in tissue degradation. Tissue inhibitor metalloproteinases-1 (TIMP-1) is a specific inhibitor of these enzymes, which is thought to regulate their action in vivo.
D J, Hodges, D C, Lee, C J, Salter, D G, Reid, G P, Harper, T E, Cawston   +5 more
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Neuroprotection from Tissue Inhibitor of Metalloproteinase-1 and its nanoparticles

Neurochemistry International, 2012
Matrix metalloproteinases (MMPs) are family of zinc dependent endopeptidases, which cleave extracellular matrix proteins, and play an important role in tissue remodelling in physiological and pathological processes. There is enhanced expression of MMPs, in particular MMP-9, during numerous pathological conditions, including epilepsy and ischemic stroke.
Chaturvedi, Mayank, Figiel, Izabela, Sreedhar, Bojja, Kaczmarek, Leszek   +3 more
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Production of tissue inhibitor of metalloproteinase-1 and -2 by cultured keratinocytes

Journal of Dermatological Science, 2000
The imbalance between metalloproteinases and their inhibitors in tissue remodelling is likely to play an important role in various pathologic conditions. In order to understand the role of keratinocytes in regulating extracellular matrix degradation in skin, we analyzed the production of metalloproteinase inhibitors in keratinocytes.
Y, Sugita, E, Morita, T, Tanaka, K, Nakamura, S, Yamamoto   +4 more
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Decreased Expression of Tissue Inhibitor of Metalloproteinase 1 in Stunned Myocardium

Journal of Surgical Research, 1998
Ultrastructural studies of stunned myocardium have shown disorganization and loss of extracellular collagen and increased collagenase activity early after ischemia and reperfusion. The interplay between matrix metalloproteinase 1 (MMP-1) and tissue inhibitor of metalloproteinase 1 (TIMP-1) regulates the turnover of cardiac extracellular matrix ...
K, Baghelai, R, Marktanner, J B, Dattilo, M P, Dattilo, E R, Jakoi, D R, Yager, R G, Makhoul, A S, Wechsler   +7 more
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Tissue inhibitor of metalloproteinases-1 in the postoperative monitoring of colorectal cancer

European Journal of Cancer, 2006
The aim of this study was to investigate whether the pre- and postoperative plasma levels of tissue inhibitor of metalloproteinases-1 (TIMP-1) were associated with outcome in colorectal cancer (CRC). Pre- and postoperative plasma TIMP-1 from 280 curatively resected CRC patients and carcinoembryonic antigen (CEA) in corresponding serum samples were ...
Holten-Andersen, Mads Nikolaj, Nielsen, Hans Jørgen, Sørensen, Steen, Jensen, Vibeke, Brünner, Nils, Christensen, Ib Jarle   +5 more
openaire   +3 more sources

Investigation of Matrix Metalloproteinase -1, 2 and tissue inhibitor of matrix metalloproteinases-1 in Endometriosis

Journal of Nanjing Medical University, 2007
Objective: To explore the role of matrix metalloproteinase-1, 2 (MMP-1, MMP-2) and tissue inhibitor of matrix metalloproteinases-1 (TIMP-1) in endometriosis. Methods: The eutopic and ectopic endometria from 40 subjects suffering from endometriosis and regular.
Rong Liu, Demin Pu, Dan Yang
openaire   +1 more source