Results 271 to 280 of about 3,998,163 (336)

Mechanically and Chemically Defined PEG Hydrogels Improve Reproducibility in Human Cardioid Development

Advanced Healthcare Materials, EarlyView.
Synthetic matrix metalloproteinase (MMP)‐degradable polyethylene glycol (PEG)‐based hydrogels are developed to investigate the influence of mechanical and biochemical cues on cardioid development. Matrix stiffness and cell adhesion motifs significantly regulate cardioid formation, chamber morphogenesis, contractile function, and cardioid transcriptome.
Yuanhui Song, Michael Seitz, Andrew Kowalczewski, Nhu Y Mai, Era Jain, Huaxiao Yang, Zhen Ma   +6 more
wiley   +1 more source

Electrically conductive lignin reinforced PAA/HA scaffolds with enhanced biological activity via polyelectrolyte multilayer coatings for tissue engineering applications. [PDF]

Sci Rep
Winters C, Culebras M, Collins MN.
europepmc   +1 more source

Pre-culture Sudan Black B treatment suppresses autofluorescence signals emitted from polymer tissue scaffolds. [PDF]

Sci Rep, 2017
Qi L, Knapton EK, Zhang X, Zhang T, Gu C, Zhao Y.   +5 more
europepmc   +1 more source

3D Microtumors Representing Ovarian Cancer Minimal Residual Disease Respond to the Fatty Acid Oxidation Inhibitor Perhexiline

Advanced Healthcare Materials, EarlyView.
Minimal residual disease (MRD) leads to cancer relapse and poor survival in ovarian cancer. The lack of representative 3D models limits therapy development. The microfluidics‐based high throughput 3D microtumor platform described here generates clinically‐relevant MRD models. The 3D microtumors recapitulate the molecular signatures of MRD from patients.
Xingyun Yang, Mara Artibani, Yongcheng Jin, Aneesh Aggarwal, Yujia Zhang, Sandra Muñoz‐Galvan, Ellina Mikhailova, Lena Rai, Nobina Mukherjee, Ravinash Krishna Kumar, Ashwag Albukhari, Shaohua Ma, Linna Zhou, Ahmed Ashour Ahmed, Hagan Bayley   +14 more
wiley   +1 more source

Biomaterial-Based Additive Manufactured Composite/Scaffolds for Tissue Engineering and Regenerative Medicine: A Comprehensive Review. [PDF]

Polymers (Basel)
Vyas J, Raytthatha N, Vyas P, Prajapati BG, Uttayarat P, Singh S, Chittasupho C.   +6 more
europepmc   +1 more source

Engineering Assembloids to Mimic Graft‐Host Skeletal Muscle Interaction

Advanced Healthcare Materials, EarlyView.
This study develops a graft‐host skeletal muscle assembloid model combining neuromuscular organoids with tissue‐engineered constructs. Pre‐seeding decellularized muscles with myogenic cells enhances cell migration and axon invasion from the organoid. The model exhibits regenerative capacity following acute damage, advancing the understanding of human ...
Lucia Rossi, Beatrice Auletta, Luigi Sartore, Marco La Placa, Giada Cecconi, Pietro Chiolerio, Edoardo Maghin, Silvia Angiolillo, Eugenia Carraro, Onelia Gagliano, Cecilia Laterza, Nicola Elvassore, Martina Piccoli, Anna Urciuolo   +13 more
wiley   +1 more source

Polydopamine-functionalized acellular fish scale scaffolds for accelerated bone tissue regeneration. [PDF]

RSC Adv
Su S, Wang R, Bai J, Gao S, Zhou R, Zhou F.   +5 more
europepmc   +1 more source

Supramolecular Additive Screening to Engineer Microfibrous Rafts for Expansion of Pluripotent Stem Cells in Dynamic Suspension

Advanced Healthcare Materials, Volume 14, Issue 11, April 25, 2025.
Segmented PCL‐bisurea (BU) polymers and BU‐peptide conjugate additives assemble into fibrous superstructures at the nanoscale through a mix‐and‐matching strategy. Different bioactivities are incorporated through variation of peptide sequences. The resulting materials are screened for their effect on stem cell adhesion and pluripotency.
Johnick F. van Sprang, Jasper G. M. Aarts, Boris Arts, Joyce E. P. Brouns, Muhabbat I. Komil, Paul A. A. Bartels, Patricia Y. W. Dankers   +6 more
wiley   +1 more source

Surface modification of electrospun polycaprolactone and zein using cold atmospheric plasma for tissue engineering applications. [PDF]

Sci Rep
Esmaeili Ranjbar A, Asadi F, Mohandesnezhad S, Vatanparast M, Mohandesnezhad S, Mirzaei MR, Noroozi Karimabad M, Fathabadi AS, Esmaeili Ranjbar F.   +8 more
europepmc   +1 more source

Engineering the Future of Restorative Clinical Peripheral Nerve Surgery

Advanced Healthcare Materials, EarlyView.
What if damaged nerves could regenerate more effectively? This review unveils cutting‐edge strategies to restore nerve function, from biomaterial scaffolds and bioactive molecules to living engineered tissues. By accelerating axonal regrowth, preserving Schwann cells, and enhancing connectivity, these approaches are reshaping nerve repair—offering new ...
Justin C. Burrell, Zarina S. Ali, Eric L. Zager, Joseph M. Rosen, Mykhailo M. Tatarchuk, D. Kacy Cullen   +5 more
wiley   +1 more source