Results 231 to 240 of about 9,169,048 (321)

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

Advanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol, Bochuan Hu, Eduard O. Bobylev, Martina Farber, Petrus C. M. Laan, Thomas J. F. Kock, Bauke Fontein, Johanna Erbani, Oscar Escalona‐Rayo, Seline S. Roose, Tom Keijer, Gabriel Forn‐Cuní, B. Ewa Snaar‐Jagalska, Leila Akkari, Joost N. H. Reek, Alexander Kros, Dennis Aschmann   +16 more
wiley   +1 more source

Advances in Bio‐Integrated Edge Computing Systems for Smart and Connected Health

Advanced Materials, EarlyView.
This review explores advances in bio‐integrated edge computing for healthcare, focusing on co‐designing computing, sensing, and energy strategies to overcome integration and power challenges for optimized, decentralized operation. ABSTRACT Recent advances in bio‐integrated healthcare technologies have enabled continuous, high‐resolution monitoring and ...
Gyuwon Kim, Seungwon Yoo, Tae Woog Kang, Yunuo Huang, Woon‐Hong Yeo   +4 more
wiley   +1 more source

Biomass DNA: An Emerging Building Block for Advanced Materials

Advanced Materials, EarlyView.
Biomass DNA is rapidly emerging from its traditional role as a genetic blueprint to serve as a versatile abundant, highly programmable polymeric building block. This review highlights the transformation of macroscopic bulk biomass DNA into next generation of functional materials, spanning from dynamic hydrogels, sustainable bioplastics, and high ...
Yuwei Hu, Itamar Willner, Li Niu
wiley   +1 more source

Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction

Advanced Materials, EarlyView.
The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu, Alison E. John, Marc A. Fernández‐Yagüe   +2 more
wiley   +1 more source

Combined T1-mapping and tissue tracking analysis predicts severity of ischemic injury following acute STEMI-an Oxford Acute Myocardial Infarction (OxAMI) study. [PDF]

Int J Cardiovasc Imaging, 2019
Wamil M, Borlotti A, Liu D, Briosa E Gala A, Bracco A, Alkhalil M, De Maria GL, Piechnik SK, Ferreira VM, Banning AP, Kharbanda RK, Neubauer S, Choudhury RP, Channon KM, Dall'Armellina E.   +14 more
europepmc   +1 more source

Near‐Infrared Imaging of H2O2 in Plants With Nanosensors Under Environmentally Changing Conditions

Advanced Materials, EarlyView.
This paper reports a ratiometric nanosensor enabling robust, multivariate detection of stress signals (H2O2) in plants, with high resistance to light fluctuations and mechanical disturbances. Single‐walled carbon nanotubes serve as the sensor, Egyptian Blue nanosheets serve as a stable reference, and plant autofluorescence serves as a label‐free ...
Jiaqi Li, Bjoern F. Hill, Chen Ma, Juliana Gretz, Tanuja Kistwal, Janus A. C. Wartmann, Justus T. Metternich, Juan Pablo Giraldo, Sebastian Kruss   +8 more
wiley   +1 more source

Blending With Insulating Polymers Enables Stable Anti‐Ambipolar Characteristics in n‐Type Organic Mixed‐Conductors for Heterogeneous Spiking Neurons

Advanced Materials, EarlyView.
A polymer blend of n‐type OMIEC P(gNDI‐gT2) with insulating PMMA yields mechanically stabilized, anti‐ambipolar organic electrochemical transistors (OECTs) with tunable ionic‐electronic transport. This blending allows low‐power, fast‐spiking heterogeneous Hodgkin–Huxley neurons, enabling biomimetic frequency deconvolution and reservoir computing, which
Zachary Laswick, Ariel Lifer, Catherine Beaumont, Liad Hayoun, Priscila Cavassin, Zeinab Hamid, Dilara Meli, William Dupont, Lincoln J. Lauhon, Iain McCulloch, Gitti L. Frey, Giovanni Maria Matrone, Jonathan Rivnay   +12 more
wiley   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

Surface Functionalization Modulates Collective Cell Behavior Near Topological Defects Induced by Topographical Patterning

Advanced Materials Interfaces, EarlyView.
Strongly adhered cells align with concentric circular ridges and exhibit predominantly tangential motion, whereas weakly adhered cells fail to follow topographical guidance and display enhanced radial inward motion. ABSTRACT Living cells establish long‐range orientational order through collective alignment, giving rise to topological defects whose ...
Prasoon Awasthi, Aniruddh Murali, Ellen Juel Pørtner, Adam Cohen Simonsen, Francesca Serra   +4 more
wiley   +1 more source

Ionic Liquid (IL) Compatibilization of Macropore‐Infused Nanocomposite Emulsion Thermosets (MINETs) for Structural Ion Transport

Advanced Materials Interfaces, EarlyView.
Macropore‐infused nanocomposite emulsion thermosets (MINETs) offer tunable multifunctionality due to their incorporation of structural resin, functional nanoparticles, and working fluid stabilized by surfactant. Here we show that if ionic liquid working fluids are introduced, structural capacitive (conductive particles) or separator (insulating ...
Bryan Llumiquinga, Iris You, Nare Cho, Madhuri Deb, Jordan C. Pierce, Kevin M. Miller, Jonathan P. Singer   +6 more
wiley   +1 more source