Results 1 to 10 of about 4,623,874 (138)

Overexpression of the Ubiquitin Specific Proteases USP43, USP41, USP27x and USP6 in Osteosarcoma Cell Lines: Inhibition of Osteosarcoma Tumor Growth and Lung Metastasis Development by the USP Antagonist PR619

open access: yesCells, 2021
Osteosarcoma (OS) is the most common malignant bone tumor in children and teenagers. In many cases, such as poor response to treatment or the presence of metastases at diagnosis, the survival rate of patients remains very low. Although in the literature,
Mélanie Lavaud   +14 more
doaj   +1 more source

Toxicity of monosodium glutamate intake on different tissues induced oxidative stress: A Review [PDF]

open access: yesJournal of Medical and Life Science, 2022
Monosodium glutamate (MSG) is one of the commonest food additives in the developed world and it is commonly used as a flavor enhancer. MSG can be found in various concentrations in numerous food products.
Aljohara Al-Otaibi   +3 more
doaj   +1 more source

Microgravity triggers ferroptosis and accelerates senescence in the MG-63 cell model of osteoblastic cells

open access: yesnpj Microgravity, 2023
In space, cells sustain strong modifications of their mechanical environment. Mechanosensitive molecules at the cell membrane regulate mechanotransduction pathways that induce adaptive responses through the regulation of gene expression, post ...
Nancy Garbacki   +10 more
doaj   +1 more source

Pro-inflammatory effects of human apatite crystals extracted from patients suffering from calcific tendinopathy

open access: yesArthritis Research & Therapy, 2021
Background Calcific tendonitis of the rotator cuff is due to carbonated apatite deposits in the shoulder tendons. During the evolution of the disease, an acute inflammatory episode may occur leading to the disappearance of the calcification.
Julien Herman   +6 more
doaj   +1 more source

The use of mesenchymal stromal cells in the treatment of coronavirus disease 2019

open access: yesJournal of Translational Medicine, 2020
More than seven months into the coronavirus disease -19 (COVID-19) pandemic, infection from the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to over 21.2 million cases and resulted in over 760,000 deaths worldwide so far.
Maurice A. Canham   +2 more
doaj   +1 more source

Hip Tenosynovial Giant Cell Tumor without Recurrence in a 9-Year Follow-Up

open access: yesCase Reports in Orthopedics, 2022
Background. Tenosynovial giant cell tumors are a benign but rare condition with potentially aggressive tumor-like traits which should be considered in young patients with monoarticular joint involvement. Case Presentation.
Seyyed-Morteza Kazemi   +1 more
doaj   +1 more source

Rapid GMP-Compliant Expansion of SARS-CoV-2–Specific T Cells From Convalescent Donors for Use as an Allogeneic Cell Therapy for COVID-19

open access: yesFrontiers in Immunology, 2021
COVID-19 disease caused by the SARS-CoV-2 virus is characterized by dysregulation of effector T cells and accumulation of exhausted T cells. T cell responses to viruses can be corrected by adoptive cellular therapy using donor-derived virus-specific T ...
Rachel S. Cooper   +9 more
doaj   +1 more source

Characterising epithelial tissues using persistent entropy [PDF]

open access: yes, 2019
In this paper, we apply persistent entropy, a novel topological statis- tic, for characterization of images of epithelial tissues. We have found out that persistent entropy is able to summarize topological and geomet- ric information encoded by ...
Atienza Martínez, María Nieves   +3 more
core   +3 more sources

A Comparative Study of Cell Culture Conditions during Conversion from Primed to Naive Human Pluripotent Stem Cells

open access: yesBiomedicines, 2022
The successful reprogramming of human somatic cells into induced pluripotent stem cells (hiPSCs) represented a turning point in the stem cell research field, owing to their ability to differentiate into any cell type with fewer ethical issues than human ...
Irene Romayor   +8 more
doaj   +1 more source

Cross‑cultural adaptation and validation of the Persian version of the new Knee Society Knee Scoring System (KSS)

open access: yesJournal of Orthopaedic Surgery and Research, 2023
Background The new Knee Society Knee Scoring System (KSS) has been widely used to assess the symptoms, satisfaction, expectations, and physical activities of patients who undergo total knee arthroplasty (TKA).
Alireza Mirahmadi   +6 more
doaj   +1 more source

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