DeepLNM: A Multimodal Model for Predicting Lymph Node Metastasis in Colorectal Cancer
Traditional diagnosis may miss positive LNM cases, and pathologists face a workload; therefore, we develop DeepLNM, a multimodal model that predicts lymph node metastasis in colorectal cancer from H&E WSIs, CT images, and text. DeepLNM is robust across internal, external, and prospective cohorts and, in a user study, improves diagnostic accuracy while ...
Zhengyu Zhang +24 more
wiley +1 more source
Developing a monitoring and assessment program with diatoms, an improved metric calculation method, and causal analysis for Big Cypress National Preserve, Florida (USA). [PDF]
Stevenson RJ, Whelan KRT, Prats MC.
europepmc +1 more source
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao +8 more
wiley +1 more source
Comment on "Construct validation of machine learning models for predicting surgical site infection risk following ankle fracture surgery". [PDF]
Fu Y.
europepmc +1 more source
This work presents a large‐cell‐compatible droplet microfluidic platform that overcomes long‐standing barriers in plant cell culture by enabling high‐fidelity encapsulation, novel multilayer 3D droplet incubation for scalable long‐term culture, and support for the full developmental progression of large plant cells.
Arman Mirmiran +10 more
wiley +1 more source
Androgen Receptor Signaling Inhibitors for Metastatic Hormone Sensitive Prostate Cancer in Asians: Indirect Comparison. [PDF]
Chen W, Yoshida S, Fujii Y.
europepmc +1 more source
This Review outlines the biological framework of entry, maintenance, and awakening in dormant minimal residual disease across gynecologic cancers. By mapping critical biological dependencies—from metabolic plasticity to microenvironment interactions—it evaluates novel interception concepts and presents a translational framework combining single‐cell ...
Shih‐Hsuan Cheng +7 more
wiley +1 more source
Structure and Dynamics in the Magnetotails of Unmagnetized and Weakly Magnetized Bodies. [PDF]
Stergiopoulou K +13 more
europepmc +1 more source
Spin Splitting Coupled Visible‐Light Driven Injection Photocurrent in Bilayer Altermagnets
Interlayer engineering in bilayer altermagnets continuously tunes visible‐light injection photocurrents, accompanied by controllable altermagnetic spin splitting. Enhanced interlayer hybridization reconstructs the band and quantum geometries, leading to opposite evolution of the normal and magnetic injection currents and establishing a direct ...
Huanhuan Yang +3 more
wiley +1 more source
Study on microwave-assisted synthesis of smart responsive magnetic Janus nanocatalysts for enhanced recovery of extra-heavy oil. [PDF]
Zhao R, Zhou D, Xu W, Zhang Y.
europepmc +1 more source

