Results 181 to 190 of about 36,631 (266)

Giant Magnetic Purcell Effect Induced by High‐Order Mie Resonances

Advanced Science, EarlyView.
High‐order Mie resonances in dielectric spheres selectively amplify magnetic dipole emission from Eu3+ emitters, producing a giant magnetic Purcell effect. Localized emitters can efficiently access high‐order resonant modes, and the low‐loss TiO2 platform enables direct far‐field observation of the enhanced emission.
Haonan Shi, Ningning Song, Anjun Huang, Zhengwen Yang, Jingbo Sun, Yongzheng Wen, Ji Zhou   +6 more
wiley   +1 more source

Prebiotic Absolute Asymmetric Synthesis of d-Ribose on Wollastonite. [PDF]

Chirality
Zhang W, Gao Y, Wang J, Deng Q, Han L, Zhang W, Fang Y.   +6 more
europepmc   +1 more source

Single‐Cell Transcriptomics and Metabolomics Reveal Glutamate Dehydrogenase as a Central Regulator of Nitrogen Metabolic Remodeling During Alkalinity Adaptation in Crustaceans

Advanced Science, EarlyView.
Single‐cell transcriptomics reveals the cellular response of Macrobrachium hainanense to carbonate alkalinity stress. Alkalinity stress impairs branchial ammonia excretion, induces mitochondrial dysfunction, and drives cell‐type‐specific changes in gills and hemocytes.
Yiting Jin, Zhimin Lv, Chao Bian, Qibin Yang, Na Zhou, Jianguang Qin, Shengming Sun   +6 more
wiley   +1 more source

A deep learning framework for efficient pathology image analysis. [PDF]

Nat Commun
Neidlinger P, Lenz T, Foersch S, Loeffler CML, Clusmann J, Gustav M, Shaktah LA, Langer R, Dislich B, Boardman LA, French AJ, Goode EL, Gsur A, Brezina S, Gunter MJ, Steinfelder R, Behrens HM, Röcken C, Harrison T, Peters U, Phipps AI, Curigliano G, Fusco N, Marra A, Hoffmeister M, Brenner H, Kather JN.   +26 more
europepmc   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

An Organoselenium Compound Induces Death in <i>Cryptococcus gattii</i> Yeast by Apoptosis and Necrosis and Shows Antifungal Efficacy in <i>Galleria mellonella</i>. [PDF]

ACS Omega
da Costa LS, de Jesus DFF, Dunkl Brujas L, de Oliveira IM, Bastos RW, Melo ASA, Santos DA, Stefani HA, Ishida K.   +8 more
europepmc   +1 more source

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

Advanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu, Yundi Wu, Shuai Zhang, Hongjuan Zhao, Jiping Zheng, Shiyang Shao, Jianqiang Chen, Xilong Wu   +7 more
wiley   +1 more source

FlyTomo: a streamlined software for on-the-fly cryo-ET data processing and diagnosis. [PDF]

Nat Commun
Zhang Z, Peng C, Zhang W, Liang J, Liu K, Chen Y, Zhang J, Liang R, Song Y, Li S.   +9 more
europepmc   +1 more source

A C‐Nucleoside Analogue of Cordycepin With High Metabolic Stability and Potent Anti‐Psoriatic Activity via Microneedle Delivery

Advanced Science, EarlyView.
This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan, Xinyue Shao, Yuanchen Zhong, Xujie Sun, Lixuan Yin, Zongyan He, Tianqun Lang, Yuanchao Xie   +7 more
wiley   +1 more source

Atomic resolution structure of human papillomavirus bound to heparin. [PDF]

Nat Commun
Langley CH, Goetschius DJ, Antolínez S, Orji EP, Bator CM, Brendle SA, Christensen ND, Hadden-Perilla JA, Hafenstein SL.   +8 more
europepmc   +1 more source