Results 51 to 60 of about 210,749 (273)

The Effects of Uniquely-Processed Titanium on Biological Systems: Implications for Human Health and Performance

Journal of Functional Biomaterials, 2014
Titanium is biocompatible and widely utilized in a variety of applications. Recently, titanium in pico-nanometer scale and soluble form (Aqua Titan) has expanded its use to applied human health and performance.
David S. Rowlands, Sarah P. Shultz, Takahiro Ogawa, Wataru Aoi, Martin Korte   +4 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

A model intercomparison of Titan's climate and low-latitude environment

Icarus (New York, N.Y. 1962), 2019
Cassini-Huygens provided a wealth of data with which to constrain numerical models of Titan. Such models have been employed over the last decade to investigate various aspects of Titan's atmosphere and climate, and several three-dimensional general ...
J. Lora, T. Tokano, J. Vatant d'Ollone, S. Lebonnois, R. Lorenz   +4 more
semanticscholar   +1 more source

Seasonal evolution of temperatures in Titan's lower stratosphere [PDF]

Icarus (New York, N.Y. 1962), 2019
The Cassini mission offered us the opportunity to monitor the seasonal evolution of Titan's atmosphere from 2004 to 2017, i.e. half a Titan year. The lower part of the stratosphere (pressures greater than 10 mbar) is a region of particular interest as ...
M. Sylvestre, N. Teanby, J. V. d’Ollone, S. Vinatier, B. Bézard, S. Lebonnois, P. Irwin   +6 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Long Period Seismology on Titan in the Presence of a Methane Clathrate Lid

Earth and Space Science
Previous 1‐D spherically symmetric seismic modeling studies have shown that in the presence of a clathrate lid on Titan significant thermal profile differences result, particularly in comparison to a pure water ice shell.
Andrea S. Bryant, Mark P. Panning, Angela G. Marusiak   +2 more
doaj   +1 more source

DSN observations of Titan [PDF]

, 1992
When using Deep Space Station (DSS)-14 in a monostatic configuration, radar observations of Titan show that Titan is a diffuse reflector with a relative radar cross section of 0.14 +/- 0.03.
Goldstein, R. M., Jurgens, R. F.
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Liquid filled canyons on Titan [PDF]

, 2016
In May 2013 the Cassini RADAR altimeter observed channels in Vid Flumina, a drainage network connected to Titan’s second largest hydrocarbon sea, Ligeia Mare. Analysis of these altimeter echoes shows that the channels are located in deep (up to ~570 m),
Birch, S. P. D., Grima, C., Hayes, A. G., Hofgartner, J. D., Lorenz, R., Mastrogiuseppe, Marco, Poggiali, Valerio, Seu, Roberto   +7 more
core   +1 more source