Results 171 to 180 of about 656,654 (332)

Tunable Enhancement of T Cell Expansion Through Modulation of Stiffness and Adhesion Receptor Engagement in an Engineered Hydrogel Platform

open access: yesAdvanced Materials, EarlyView.
We develop a hydrogel scaffold with controlled substrate stiffness and ligand functionalization for cell culture. Stiff substrates presenting CD3/CD28/CD2 ligands induce 2000‐fold expansion of T cells; this is 68% greater than the clinical standard (Dynabeads) and the first hydrogel capable of large‐scale expansion. Although expanding at a lower yield,
Niroshan Anandasivam   +5 more
wiley   +1 more source

Intrinsically Disordered Protein‐Inspired Nanovector‐Based Coacervates for the Direct Cytosolic Transport of Biomacromolecules

open access: yesAdvanced Materials, EarlyView.
Intrinsically disordered protein‐inspired nanovectors (IDP‐NVs) form stable nanocoacervates (NCs) with diverse biomacromolecules. In situ conformational changes confer stability and adaptability to NCs under dynamically changing physiological conditions.
Soyeong Jin   +14 more
wiley   +1 more source

Early Results of Implementing Rapid Methadone Titration for Hospitalized Patients: A Case Series [PDF]

open access: hybrid
Marlene Martín   +8 more
openalex   +1 more source

Arresting Microphase Separation Encodes Material Mechanics by Sculpting Microarchitectures and Local Polymer Enrichment

open access: yesAdvanced Materials, EarlyView.
Microarchitecture sculpting via phase separation programs hydrogel mechanics by creating globular, inverse globular, and spinodal structures. Spinodal architectures deliver superior toughness and energy dissipation, while ionic modulation through single polymer phase separation offers a simple, scalable route to tune mechanical properties ...
Castro Johnbosco   +9 more
wiley   +1 more source

Unravelling the Secret of Sulfur Confinement and High Sulfur Utilization in Hybrid Sulfur‐Carbons

open access: yesAdvanced Materials, EarlyView.
Thermal condensation of inverse vulcanized sulfur‐carbon hybrids enables a bottom‐up sulfur confinement strategy, in which a protective carbon phase is progressively constructed around sulfur species. The resulting carbon nanodomains covalently tether sulfur chains and stabilize radical intermediates. This integrated architecture effectively suppresses
Tim Horner   +9 more
wiley   +1 more source

Comprehensive Understanding of Accelerated Kinetics Driven by Anion–Diluent Dynamics Enabling Wide Temp Operation in Dual‐Ion Batteries

open access: yesAdvanced Materials, EarlyView.
The transient interactions between TFSI− anions and a diluent within an anion‐dictated electrolyte are revealed, which can reduce interfacial reorganization energy, thereby accelerating ion kinetics and markedly facilitating sustainable anion storage in high‐voltage graphite cathodes for dual‐ion batteries at fast charge and wide temperature range ...
Sungho Kim   +9 more
wiley   +1 more source

A hybrid strategy combining solution NMR spectroscopy and isothermal titration calorimetry to characterize protein-nanodisc interaction

open access: hybrid, 2021
Toshihiko Sugiki   +7 more
openalex   +1 more source

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