Results 221 to 230 of about 1,901,345 (335)

Safe focused ultrasound-mediated blood-brain barrier opening is driven primarily by transient reorganization of tight junctions. [PDF]

Commun Eng
Noel RL, Kugelman T, Karakatsani ME, Shahriar S, Willner MJ, Jimenez DA, Choi CS, Nimi Y, Ji R, Agalliu D, Konofagou EE.   +10 more
europepmc   +1 more source

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

Gypenoside XLIX ameliorates diabetic retinopathy by downregulating prostaglandin-endoperoxide synthase 2 in retinal pigment epithelium cells to inhibit ferroptosis and preserve tight junction integrity. [PDF]

Front Pharmacol
Gu J, Zhu M, Li L, Cao X, Yu X, Huang X, Huang L, Cai Q, Zhu Y, Li W, Wang Y.   +10 more
europepmc   +1 more source

Use of Yokukansan (TJ‐54) in the treatment of neurological disorders: a review

Phytotherapy Research, 2010
S. Caíres, Vanessa Steenkamp
semanticscholar   +1 more source

Mechanistic Design of Graphdiyne‐Based Multimodal Sensing Integrating Machine Learning and Photothermal Dynamics for Precision Recognition and On‐Demand Inactivation

Advanced Science, EarlyView.
A triple‐mode theranostic platform enables integrated electrochemical, colorimetric, and photothermal detection of bacterial infection. Glucose oxidation triggers H2O2 generation and TMB oxidation to oxTMB, producing color and thermal signals under 808 nm NIR irradiation.
Jing Xu, Hanxiao Chen, Liucun Yin, Yifang Tao, Qichen Yuan, Hong Wang, Huan Pang, Junyan Teng, Li Xue   +8 more
wiley   +1 more source

Targeting epigenetic remodeling of the blood-brain barrier: current knowledge for drug therapy. [PDF]

Epigenomics
Akhoury M, Vegara N, Stamatovic SM, Keep RF, Andjelkovic AV.   +4 more
europepmc   +1 more source

Commentary: Teaching dogs new tricks [PDF]

, 2004
Cole, TJ
core  

Cancer‐Associated Fibroblast‐Derived Sphingosine‐1‐Phosphate Activates a MALL–SDC4 Axis to Facilitate Perineural Invasion in Pancreatic Cancer

Advanced Science, EarlyView.
CAF‐derived S1P activates the S1PR3‐JNK‐Jun signaling pathway, thereby transcriptionally upregulating MALL expression in cancer cells. MALL increases the cell‐surface abundance of SDC4 by promoting its recycling and restricting its lysosomal degradation, which in turn enhances RhoA‐p‐MLC2‐dependent amoeboid invasion and SDC4‐PTN axis‐mediated cancer ...
Wang Peng, Mengdie Cao, Hai Huang, Shuya Bai, Luyao Liu, Jingwen Liang, Haochen Cui, Qiaodan Zhou, Shiru Chen, Jiamei Jiang, Luoxia Liu, Zhou Luan, Wei Chen, Si Xiong, Ronghua Wang, Bin Cheng, Yuchong Zhao   +16 more
wiley   +1 more source

Architecture, permeability, disruption dynamics and remodeling of tight junction proteins: Implications for performance, health, and welfare of the broiler chicken. [PDF]

Poult Sci
Hossain ME, Munni MB, Islam S.
europepmc   +1 more source

Regulation of tight junction permeability by intestinal bacteria and dietary components.

Journal of NutriLife, 2011
Dulantha Ulluwishewa, R. Anderson, W. McNabb, P. Moughan, J. Wells, N. Roy   +5 more
semanticscholar   +1 more source