Results 181 to 190 of about 218,060 (295)

Telomere length promotes colorectal cancer through dual parallel pathways involving growth signaling and protein metabolism. [PDF]

Trop Med Health
Liu C, Wang F, Zhang Z, Su Q, Li Y.
europepmc   +1 more source

Photoelectron Spectroscopic Study of Tl-2201, Tl-2212, Tl-2223, and Tl-2234 High-Tc Superconductors

Photoelectron Spectroscopic Study of Tl-2201, Tl-2212, Tl-2223, and Tl-2234 High-Tc Superconductors
identifier:oai:t2r2.star.titech.ac.jp ...
openaire  

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

Parental Age Effects on Offspring Telomere Length Across Vertebrates: A Meta-Analysis. [PDF]

Mol Ecol
Vlasova M, Sun Y, Chik HYJ, Dugdale HL.
europepmc   +1 more source

p16Ink4a‐Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway

Advanced Science, EarlyView.
This study found that, following the long‐term CCl4 treatment, p16high hepatocytes appeared in zone 3, spatially co‐localizing with fibrotic areas. A specific cluster of p16high hepatocytes upregulated CTF1/LIF expression which induced HSC activation and further liver fibrosis, as revealed by single cell transcriptomic analysis.
Koji Nishikawa, Teh‐Wei Wang, Satoshi Kawakami, Shota Tanimoto, Kiyoshi Yamaguchi, Taketomo Kido, Masamichi Kimura, Tsunekazu Hishima, Yuki T. Okamura, Satotaka Omori, Takumi Iritani, Toshikaze Chiba, Takehiro Jimbo, Michio Katano, Kansuporn Kamataki, Ryoichi Yokoyama, Eigo Shimizu, Kiminori Kimura, Satoshi Yamzaki, Seiya Imoto, Yoichi Furukawa, Atsushi Miyajima, Yoshikazu Johmura, Makoto Nakanishi   +23 more
wiley   +1 more source

Triptolide combined with arsenic trioxide induces apoptosis of myelodysplastic syndrome cells by inhibiting the NF-κB signaling pathway. [PDF]

Medicine (Baltimore)
Sheng L, Zhu Y, Wen Z, Fang M, Gu S, Ye L, Hua H.   +6 more
europepmc   +1 more source

Studies on the monoamine oxidase(MAO) inhibitory potency of TL-1, isolated from a fungus, Talaromyces luteus.

, 1989
Yumiko Satoh, Mikio Yamazaki
openalex   +2 more sources

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Surviving Allchar: arsenic and thallium tolerance and distribution in Viola metallophytes. [PDF]

Ann Bot
Jakovljević K, Salinitro M, Bačeva Andonovska K, Mišljenović T, Brueckner D, van der Ent A.   +5 more
europepmc   +1 more source

Activity Measurements of Liquid Tl-In Alloys by an EMF Method Using Zirconia Electrolytes

, 1992
Kazuo Kameda, Katsunori Yamaguchi
openalex   +2 more sources