Results 201 to 210 of about 218,060 (295)

LLM-Assisted Scoping Review of Artificial Intelligence in Brazilian Public Health: Lessons from Transfer and Federated Learning for Resource-Constrained Settings. [PDF]

Int J Environ Res Public Health
Borges FT, Machado GDM, Santana MA, Sancho KA, França GVA, Santos WPD, Siqueira CEG.   +6 more
europepmc   +1 more source

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

Data-Efficient Deep Learning Framework for Urolithiasis Detection Using Transfer and Self-Supervised Learning. [PDF]

Int Neurourol J
Kim JS, Eun SJ.
europepmc   +1 more source

5′tRF‐GlyGCC Promotes Breast Cancer Progression via LDHA‐Mediated Glycolysis and Macrophage Polarization

Advanced Science, EarlyView.
5’tRF‐GlyGCC promotes breast cancer malignancy by binding to LDHA. This interaction, facilitated by FGFR1 and LDHA phosphorylation, enhances glycolysis. Additionally, 5’tRF‐GlyGCC/LDHA signaling recruits and polarizes macrophages into a pro‐tumor M2 state via CCL7, thus remodeling the tumor microenvironment.
Cheng Yi, Yunqing Lu, Xing Chang, Ying Wang, Jiawang Zhou, Guoyou Xie, Lijun Tao, Zhaotong Wang, Yifan Tian, Lihong Wang, Feng Tang, Yijing Zheng, Xinchen Yue, Jinping Lei, Xiansong Wang, Lichen Ge, Zhuojia Chen, Hongsheng Wang   +17 more
wiley   +1 more source

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

Advanced Science, EarlyView.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu, Jing Xun, Bin Liu, Xiaolin Jiang, Yingdi Han, Huichao Yang, Qi Gao, Ruifang Gao, Aimin Zhang, Xueliang Wu, Dapeng Zhang, Dihua Li, Tian Li, Shimin Yang, Ximo Wang, Xiangyang Yu, Qi Zhang   +16 more
wiley   +1 more source

Role of Chest CT Radiomics in Differentiating Tumorlets and Granulomas: A Preliminary Study. [PDF]

J Clin Med
Siciliani A, Guido G, De Santis D, Bracci B, Masci B, Faggiano A, Mikovic N, Paravani P, Martiradonna M, Palmeri F, De Dominicis C, Mancini M, Zerunian M, Trabalza Marinucci B, Maurizi G, Rendina EA, Francone M, Laghi A, Ibrahim M, Caruso D.   +19 more
europepmc   +1 more source

Interpretation of²⁰¹Tl Myocardial Scan in Ischemic Heart Disease

, 1984
Kyu Hyung Ryu, Wang Seong Ryu, Young Jung Kim, Myoung Mook Lee, Myung Chul Lee, Yun Sik Choi, Jungdon Seo, Young Woo Lee   +7 more
openalex   +1 more source

AI‐Optimized Vanadium Oxide Multilayers for More Than 20‐fold Enhancement in Bolometric Performance

Advanced Science, EarlyView.
Machine‐learning‐optimized WxV1‐xOy multilayer thin films with graded doping achieve a high TCR (7.3 % K−1), reduced hysteresis, and low noise under CMOS‐compatible growth conditions. This approach overcomes the long‐standing trade‐off in microbolometers between linear response and performance, offering a universal bolometric parameter greatly enhanced
Jin‐Hyun Choi, Hyoung‐Taek Lee, Jeonghoon Kim, Miju Park, Seungjoon Sun, Gye‐Hyeon Kim, Myung‐Ho Kwon, Hyeong‐Ryeol Park, Changhee Sohn   +8 more
wiley   +1 more source

Bacterial community diversity and potential eco-physiological roles in toxigenic blooms composed of <i>Microcystis</i>, <i>Aphanizomenon</i> or <i>Planktothrix</i>. [PDF]

Front Microbiol
Mankiewicz-Boczek J, Font-Nájera A, Gin KY, Graham JL, Strapagiel D, Gorney RM, Kok JWK, Te SH, Kluska M, Skóra M, Seweryn M, López-Hun F.   +11 more
europepmc   +1 more source

Mutual Exclusion Analysis Shows that DUSP9 Negatively Regulates PD‐L1 Expression and Acts as a Target to Enhance Anti‐PD‐1 Efficacy

Advanced Science, EarlyView.
A mutually exclusive screening system is established to identify negative regulators of highly plastic genes. Dual specificity phosphatase (DUSP9) is a novel negative regulatory molecule of PD‐L1 by dephosphorylating STAT3, and acts as a target molecule in combination with PD‐1 antibody for tumor immunotherapy and a new clinical biomarker for ...
Yuzhe Hu, Ling Tang, Zheng Kuang, Danyi Huang, Ting Li, Gaofei Yin, Yingyu Chen, Wei Guo, Wenling Han, Pingzhang Wang   +9 more
wiley   +1 more source